Description : Ubiquitin-like modifier involved in autophagy and the Cvt pathway; conserved; conjugated to Atg5p to form a complex involved in Atg8p lipidation; Atg5p-Atg12p conjugate enhances E2 activity of Atg3p by rearranging its catalytic site, also forms a complex with Atg16p; the Atg5-Atg12/Atg16 complex binds to membranes and is essential for autophagosome formation [Source:SGD;Acc:S000000421]
Gene families : OG_03_0003396 (OF) Phylogenetic Tree(s): OG0003396_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
Type | Description | Actions |
---|---|---|
Neighborhood | HRR: YBR217W | |
Cluster | HCCA: Cluster_6 |
Target | Alias | Description | ECC score | Gene Family Method | Actions |
---|---|---|---|---|---|
CBF85511 | No alias | Autophagy-related protein 12 | 0.02 | OF |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
BP | GO:0000045 | autophagosome assembly | IEA | Interproscan |
CC | GO:0005737 | cytoplasm | IEA | Interproscan |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
No Predicted GO terms available for this sequence |
InterPro domains | Description | Start | Stop |
---|---|---|---|
IPR007242 | Atg12 | 103 | 186 |
No external refs found! |