YBR217W


Description : Ubiquitin-like modifier involved in autophagy and the Cvt pathway; conserved; conjugated to Atg5p to form a complex involved in Atg8p lipidation; Atg5p-Atg12p conjugate enhances E2 activity of Atg3p by rearranging its catalytic site, also forms a complex with Atg16p; the Atg5-Atg12/Atg16 complex binds to membranes and is essential for autophagosome formation [Source:SGD;Acc:S000000421]


Gene families : OG_03_0003396 (OF) Phylogenetic Tree(s): OG0003396_tree

Sequence : coding (download), protein (download)


Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood HRR: YBR217W
Cluster HCCA: Cluster_6

Target Alias Description ECC score Gene Family Method Actions
CBF85511 No alias Autophagy-related protein 12 0.02 OF

Type GO Term Name Evidence Source
BP GO:0000045 autophagosome assembly IEA Interproscan
CC GO:0005737 cytoplasm IEA Interproscan
Type GO Term Name Evidence Source

No Predicted GO terms available for this sequence

InterPro domains Description Start Stop
IPR007242 Atg12 103 186
No external refs found!