YMR304W

Description : Ubiquitin-specific protease involved in protein deubiquitination; forms a complex with AAA peroxins Pex1p and Pex6p; deubiquitinates mono- and polyubiquitinated forms of Pex5p; deubiquitinates Clb5p, counteracting APC activity, and facilitating both Clb5p accumulation and S phase entry; physically interacts with anaphase-promoting complex/cyclosome (APC/C) activator, Cdh1p; catalytic activity regulated by an N-terminal TRAF-like domain and and C-terminal sequences [Source:SGD;Acc:S000004920]

Gene families : OG_03_0001240 (OF) Phylogenetic Tree(s): OG0001240_tree

Sequence : coding (download), protein (download)

Download

Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: YMR304W
Cluster	HCCA: Cluster_23

Target	Alias	Description	ECC score	Gene Family Method
AGV14889	No alias	ubiquitin carboxyl-terminal hydrolase...	0.06	OF
AOA69912	No alias	Ubiquitin carboxyl-terminal hydrolase, C-terminal	0.1	OF
CAG81087	No alias	Peptidase C19, ubiquitin carboxyl-terminal hydrolase	0.07	OF
EAA31950	No alias	Ubiquitin carboxyl-terminal hydrolase 7, ICP0-binding domain	0.03	OF
EAL85980	No alias	ubiquitin C-terminal hydrolase (HAUSP), putative	0.08	OF
EAU88443	No alias	ubiquitin carboxyl-terminal hydrolase 5	0.05	OF
EAU90382	No alias	ubiquitin carboxyl-terminal hydrolase 5	0.01	OF
EGR44904	No alias	MATH/TRAF domain	0.02	OF
ESU13640	No alias	Peptidase C19, ubiquitin carboxyl-terminal hydrolase	0.04	OF
KHC82031	No alias	ubiquitin carboxyl-terminal hydrolase...	0.07	OF
MGG_07468T0	No alias	Ubiquitin C-terminal hydrolase...	0.03	OF
POW13814	No alias	Peptidase C19, ubiquitin carboxyl-terminal...	0.02	OF
SPBC713.02c.1	No alias	ubiquitin C-terminal hydrolase Ubp15...	0.05	OF
SPCC188.08c.1	No alias	ubiquitin C-terminal hydrolase Ubp5...	0.05	OF

Type	GO Term	Name	Evidence	Source
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
BP	GO:0006464	cellular protein modification process	None	Extended
BP	GO:0006508	proteolysis	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
MF	GO:0008233	peptidase activity	None	Extended
MF	GO:0008234	cysteine-type peptidase activity	None	Extended
BP	GO:0009987	cellular process	None	Extended
BP	GO:0016579	protein deubiquitination	IEA	Interproscan
MF	GO:0016787	hydrolase activity	None	Extended
BP	GO:0019538	protein metabolic process	None	Extended
MF	GO:0019783	ubiquitin-like protein-specific protease activity	None	Extended
BP	GO:0036211	protein modification process	None	Extended
MF	GO:0036459	thiol-dependent ubiquitinyl hydrolase activity	IEA	Interproscan
BP	GO:0043170	macromolecule metabolic process	None	Extended
BP	GO:0043412	macromolecule modification	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044260	cellular macromolecule metabolic process	None	Extended
BP	GO:0044267	cellular protein metabolic process	None	Extended
MF	GO:0070011	peptidase activity, acting on L-amino acid peptides	None	Extended
BP	GO:0070646	protein modification by small protein removal	None	Extended
BP	GO:0070647	protein modification by small protein conjugation or removal	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
MF	GO:0101005	ubiquitinyl hydrolase activity	None	Extended
MF	GO:0140096	catalytic activity, acting on a protein	None	Extended
BP	GO:1901564	organonitrogen compound metabolic process	None	Extended

Toggle parental

Type	GO Term	Name	Evidence	Source
No Predicted GO terms available for this sequence

InterPro domains	Description	Start	Stop
IPR001394	Peptidase_C19_UCH	205	533
IPR029346	USP_C	966	1217
IPR024729	USP7_ICP0-binding_dom	649	936

External Links

No external refs found!

YMR304W

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation