Description : Mitochondrial inorganic pyrophosphatase; required for mitochondrial function and possibly involved in energy generation from inorganic pyrophosphate; human ortholog, PPA2, functionally complements the null mutant; mutations in human PPA2 cause a mitochondrial disease resulting in sudden unexpected cardiac arrest in infants [Source:SGD;Acc:S000004880]
Gene families : OG_03_0001342 (OF) Phylogenetic Tree(s): OG0001342_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
Type | Description | Actions |
---|---|---|
Neighborhood | HRR: YMR267W | |
Cluster | HCCA: Cluster_27 |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
MF | GO:0000287 | magnesium ion binding | IEA | Interproscan |
MF | GO:0004427 | inorganic diphosphatase activity | IEA | Interproscan |
CC | GO:0005737 | cytoplasm | IEA | Interproscan |
BP | GO:0006796 | phosphate-containing compound metabolic process | IEA | Interproscan |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
No Predicted GO terms available for this sequence |
InterPro domains | Description | Start | Stop |
---|---|---|---|
IPR008162 | Pyrophosphatase | 78 | 264 |
No external refs found! |