Description : Ubiquitin-binding protein; ER membrane protein that recruits and integrates the ubiquitin-conjugating enzyme Ubc7p into ER membrane-bound ubiquitin ligase complexes that function in the ER-associated degradation (ERAD) pathway for misfolded proteins; contains a CUE domain that binds ubiquitin to facilitate intramolecular monoubiquitination and to promote diubiquitin elongation, facilitating polyubiquitin chain formation [Source:SGD;Acc:S000004877]
Gene families : OG_03_0003357 (OF) Phylogenetic Tree(s): OG0003357_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
Type | Description | Actions |
---|---|---|
Neighborhood | HRR: YMR264W | |
Cluster | HCCA: Cluster_40 |
Target | Alias | Description | ECC score | Gene Family Method | Actions |
---|---|---|---|---|---|
EFI26670 | No alias | Ubiquitin system component CUE | 0.02 | OF | |
ESU11018 | No alias | Ubiquitin system component CUE | 0.04 | OF |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
MF | GO:0005515 | protein binding | IEA | Interproscan |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
No Predicted GO terms available for this sequence |
No external refs found! |