YMR200W


Description : Molecular chaperone involved in protein folding in ER; mutation causes defects in cell wall synthesis and lysis of autophagic bodies, suppresses tor2 mutations, and is synthetically lethal with kar2-1 and with rot2 mutations; involved in N-linked glycosylation and O-mannosylation; transmembrane helix Ser250 is essential for Rot1p to interact with other membrane components and exert its functional role, avoiding exposure of Ser H-bonding group at lipid-exposed surface [Source:SGD;Acc:S000004813]


Gene families : OG_03_0004445 (OF) Phylogenetic Tree(s): OG0004445_tree

Sequence : coding (download), protein (download)


Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood HRR: YMR200W
Cluster HCCA: Cluster_46

Target Alias Description ECC score Gene Family Method Actions
AOA65822 No alias Protein Rot1 0.03 OF

Type GO Term Name Evidence Source
CC GO:0005783 endoplasmic reticulum IEA Interproscan
BP GO:0006458 'de novo' protein folding IEA Interproscan
Type GO Term Name Evidence Source

No Predicted GO terms available for this sequence

InterPro domains Description Start Stop
IPR019623 Rot1 31 253
No external refs found!