Description : Polo-like kinase; controls targeting and activation of Rho1p at cell division site via Rho1p guanine nucleotide exchange factors; regulates Spc72p; also functions in adaptation to DNA damage during meiosis; regulates the shape of the nucleus and expansion of the nuclear envelope during mitosis; similar to Xenopus Plx1 and S. pombe Plo1p; human homologs PLK1, PLK3 can each complement yeast cdc5 thermosensitive mutants [Source:SGD;Acc:S000004603]

Gene families : OG_03_0002655 (OF) Phylogenetic Tree(s): OG0002655_tree

Sequence : coding (download), protein (download)

Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type Description Actions
Neighborhood HRR: YMR001C
Cluster HCCA: Cluster_3

Target Alias Description ECC score Gene Family Method Actions
AFR98103 No alias PLK/PLK1 protein kinase;Protein kinase domain;POLO box... 0.03 OF
AOA69136 No alias POLO box domain 0.07 OF
CAG81504 No alias POLO box domain 0.06 OF
CAK97319 No alias Protein kinase domain 0.05 OF
CBF85111 No alias plkA description 0.04 OF
EAA35457 No alias POLO box domain 0.04 OF
EAL85331 No alias serine/threonine protein kinase, putative 0.07 OF
EGR50819 No alias Protein kinase domain 0.03 OF
ESU06566 No alias Protein kinase domain 0.04 OF
KHC82885 No alias cell cycle serine/threonine-protein kinase... 0.07 OF
MGG_09960T0 No alias PLK protein kinase [Source:UniProtKB/TrEMBL;Acc:G4MRN5] 0.03 OF
SPAC23C11.16.1 No alias Polo kinase Plo1 [Source:PomBase;Acc:SPAC23C11.16] 0.03 OF

Type GO Term Name Evidence Source
MF GO:0004672 protein kinase activity IEA Interproscan
MF GO:0005515 protein binding IEA Interproscan
MF GO:0005524 ATP binding IEA Interproscan
BP GO:0006468 protein phosphorylation IEA Interproscan
Type GO Term Name Evidence Source

No Predicted GO terms available for this sequence

InterPro domains Description Start Stop
IPR000959 POLO_box_dom 621 691
IPR000959 POLO_box_dom 521 585
IPR000719 Prot_kinase_dom 82 337
No external refs found!