Description : Mitofusin; integral membrane protein involved in mitochondrial outer membrane tethering and fusion; role in mitochondrial genome maintenance; efficient tethering and degradation of Fzo1p requires an intact N-terminal GTPase domain; targeted for destruction by the ubiquitin ligase SCF-Mdm30p and the cytosolic ubiquitin-proteasome system [Source:SGD;Acc:S000000383]
Gene families : OG_03_0002007 (OF) Phylogenetic Tree(s): OG0002007_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
| Type | Description | Actions |
|---|---|---|
| Neighborhood | HRR: YBR179C | |
| Cluster | HCCA: Cluster_68 |
| Target | Alias | Description | ECC score | Gene Family Method | Actions |
|---|---|---|---|---|---|
| AOA67767 | No alias | Dynamin superfamily | 0.05 | OF | |
| CAG77989 | No alias | Dynamin superfamily | 0.06 | OF | |
| EAA27464 | No alias | Dynamin superfamily | 0.02 | OF | |
| EBA27429 | No alias | transmembrane GTPase Fzo1, putative | 0.02 | OF | |
| EDN91123 | No alias | Dynamin superfamily | 0.02 | OF | |
| ESU09024 | No alias | Dynamin superfamily | 0.02 | OF | |
| KHC76518 | No alias | small GTP-binding protein domain;Dynamin family | 0.03 | OF | |
| MGG_05209T0 | No alias | Transmembrane GTPase fzo1 [Source:UniProtKB/TrEMBL;Acc:G4N536] | 0.02 | OF |
| Type | GO Term | Name | Evidence | Source |
|---|---|---|---|---|
No GO annotation available for this sequence |
| Type | GO Term | Name | Evidence | Source |
|---|---|---|---|---|
No Predicted GO terms available for this sequence |
| InterPro domains | Description | Start | Stop |
|---|---|---|---|
| IPR022812 | Dynamin_SF | 190 | 370 |
| No external refs found! |