Description : Thioredoxin peroxidase; acts as both ribosome-associated and free cytoplasmic antioxidant; self-associates to form high-molecular weight chaperone complex under oxidative stress; chaperone activity essential for growth in zinc deficiency; required for telomere length maintenance; binds and modulates Cdc19p activity; protein abundance increases, forms cytoplasmic foci during DNA replication stress; TSA1 has a paralog, TSA2, that arose from the whole genome duplication [Source:SGD;Acc:S000004490]

Gene families : OG_03_0005492 (OF) Phylogenetic Tree(s): OG0005492_tree

Sequence : coding (download), protein (download)

Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type Description Actions
Neighborhood HRR: YML028W
Cluster HCCA: Cluster_19

Target Alias Description ECC score Gene Family Method Actions
AOA66960 No alias Peroxiredoxin, C-terminal 0.06 OF
CAG83166 No alias Alkyl hydroperoxide reductase subunit C/ Thiol specific... 0.02 OF
KHC79175 No alias peroxiredoxin TSA1;AhpC/TSA family;C-terminal domain of... 0.03 OF

Type GO Term Name Evidence Source
MF GO:0016209 antioxidant activity IEA Interproscan
MF GO:0016491 oxidoreductase activity IEA Interproscan
MF GO:0051920 peroxiredoxin activity IEA Interproscan
BP GO:0055114 oxidation-reduction process IEA Interproscan
Type GO Term Name Evidence Source

No Predicted GO terms available for this sequence

InterPro domains Description Start Stop
IPR019479 Peroxiredoxin_C 158 192
IPR000866 AhpC/TSA 5 137
No external refs found!