YLR449W


Description : Peptidyl-prolyl cis-trans isomerase (PPIase); nuclear proline isomerase; affects expression of multiple genes via its role in nucleosome assembly; catalyzes isomerization of proline residues in histones H3 and H4, which affects lysine methylation of those histones; PPIase domain acts as a transcriptional repressor when tethered to DNA by lexA, and repressor activity is dependent on PPIase activity; contains a nucleoplasmin-like fold and can form pentamers [Source:SGD;Acc:S000004441]


Gene families : OG_03_0002142 (OF) Phylogenetic Tree(s): OG0002142_tree

Sequence : coding (download), protein (download)


Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood HRR: YLR449W
Cluster HCCA: Cluster_16

Target Alias Description ECC score Gene Family Method Actions
AFR94997 No alias FK506-binding protein 4;Nucleoplasmin-like... 0.06 OF
AOA67928 No alias Nucleoplasmin-like domain 0.1 OF
CAK40708 No alias FKBP-type peptidyl-prolyl cis-trans isomerase 0.07 OF
CBF75117 No alias FK506-binding protein 4 0.07 OF
EAA34497 No alias Nucleoplasmin-like domain 0.07 OF
EAL88709 No alias FKBP-type peptidyl-prolyl isomerase, putative 0.1 OF
EAU91426 No alias peptidylprolyl isomerase 0.09 OF
EED48597 No alias FKBP-type peptidyl-prolyl isomerase, putative 0.04 OF
EGR51536 No alias FKBP-type peptidyl-prolyl cis-trans isomerase domain 0.09 OF
ESU06331 No alias FK506-binding protein 0.1 OF
KHC83156 No alias FK506-binding protein 3;FKBP-type peptidyl-prolyl... 0.12 OF
MGG_04476T0 No alias FK506-binding protein 4 [Source:UniProtKB/TrEMBL;Acc:G4MKI9] 0.03 OF
POW17628 No alias FKBP-type peptidyl-prolyl cis-trans isomerase... 0.03 OF
SPAC27F1.06c.1 No alias FKBP-type peptidyl-prolyl cis-trans isomerase... 0.07 OF
SPBC1347.02.1 No alias FKBP-type peptidyl-prolyl cis-trans isomerase... 0.06 OF

Type GO Term Name Evidence Source
MF GO:0003755 peptidyl-prolyl cis-trans isomerase activity IEA Interproscan
Type GO Term Name Evidence Source

No Predicted GO terms available for this sequence

InterPro domains Description Start Stop
IPR001179 PPIase_FKBP_dom 301 389
IPR041232 NPL 10 164
No external refs found!