Description : Peptidyl-prolyl cis-trans isomerase (PPIase); nuclear proline isomerase; affects expression of multiple genes via its role in nucleosome assembly; catalyzes isomerization of proline residues in histones H3 and H4, which affects lysine methylation of those histones; PPIase domain acts as a transcriptional repressor when tethered to DNA by lexA, and repressor activity is dependent on PPIase activity; contains a nucleoplasmin-like fold and can form pentamers [Source:SGD;Acc:S000004441]
Gene families : OG_03_0002142 (OF) Phylogenetic Tree(s): OG0002142_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
Type | Description | Actions |
---|---|---|
Neighborhood | HRR: YLR449W | |
Cluster | HCCA: Cluster_16 |
Target | Alias | Description | ECC score | Gene Family Method | Actions |
---|---|---|---|---|---|
AFR94997 | No alias | FK506-binding protein 4;Nucleoplasmin-like... | 0.06 | OF | |
AOA67928 | No alias | Nucleoplasmin-like domain | 0.1 | OF | |
CAK40708 | No alias | FKBP-type peptidyl-prolyl cis-trans isomerase | 0.07 | OF | |
CBF75117 | No alias | FK506-binding protein 4 | 0.07 | OF | |
EAA34497 | No alias | Nucleoplasmin-like domain | 0.07 | OF | |
EAL88709 | No alias | FKBP-type peptidyl-prolyl isomerase, putative | 0.1 | OF | |
EAU91426 | No alias | peptidylprolyl isomerase | 0.09 | OF | |
EED48597 | No alias | FKBP-type peptidyl-prolyl isomerase, putative | 0.04 | OF | |
EGR51536 | No alias | FKBP-type peptidyl-prolyl cis-trans isomerase domain | 0.09 | OF | |
ESU06331 | No alias | FK506-binding protein | 0.1 | OF | |
KHC83156 | No alias | FK506-binding protein 3;FKBP-type peptidyl-prolyl... | 0.12 | OF | |
MGG_04476T0 | No alias | FK506-binding protein 4 [Source:UniProtKB/TrEMBL;Acc:G4MKI9] | 0.03 | OF | |
POW17628 | No alias | FKBP-type peptidyl-prolyl cis-trans isomerase... | 0.03 | OF | |
SPAC27F1.06c.1 | No alias | FKBP-type peptidyl-prolyl cis-trans isomerase... | 0.07 | OF | |
SPBC1347.02.1 | No alias | FKBP-type peptidyl-prolyl cis-trans isomerase... | 0.06 | OF |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
MF | GO:0003755 | peptidyl-prolyl cis-trans isomerase activity | IEA | Interproscan |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
No Predicted GO terms available for this sequence |
No external refs found! |