1. Home
  2. Species
  3. Saccharomyces cerevisiae
  4. Sequence
  5. YLR430W

YLR430W


Description : ATP-dependent 5' to 3' RNA/DNA and DNA helicase; subunit of the exosome-associated Nrd1p complex that mediates 3' end formation of snRNAs, snoRNAs, CUTs and some mRNAs; helicase-independent role in transcription-coupled repair; coordinates replication with transcription, associating with moving forks and preventing errors that occur when forks encounter transcribed regions; homolog of Senataxin, implicated in Ataxia-Oculomotor Apraxia 2 and a dominant form of juvenile ALS [Source:SGD;Acc:S000004422]


Gene families : OG_03_0002008 (OF) Phylogenetic Tree(s): OG0002008_tree

Sequence : coding (download), protein (download)


Download

Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood HRR: YLR430W
Cluster HCCA: Cluster_12

Target Alias Description ECC score Gene Family Method Actions
AFR98953 No alias senataxin;AAA domain;SEN1 N terminal 0.08 OF
AOA67454 No alias DNA2/NAM7 helicase-like, AAA domain 0.2 OF
CAG84178 No alias DNA2/NAM7 helicase-like, AAA domain 0.14 OF
CAK41330 No alias AAA domain 0.16 OF
EAA35422 No alias DNA2/NAM7 helicase, AAA domain 0.1 OF
EAL85833 No alias tRNA-splicing endonuclease, putative 0.25 OF
EAU85901 No alias helicase sen1 0.06 OF
EDO03114 No alias DNA2/NAM7 helicase-like, AAA domain 0.1 OF
EED86081 No alias Helicase Sen1, N-terminal 0.03 OF
EGR49808 No alias Helicase Sen1, N-terminal 0.19 OF
ESU14667 No alias Helicase Sen1, N-terminal 0.1 OF
KHC79019 No alias senataxin;SEN1 N terminal;AAA domain 0.09 OF
MGG_02784T0 No alias DNA-binding protein SMUBP-2 [Source:UniProtKB/TrEMBL;Acc:G4NIZ8] 0.03 OF
POW17321 No alias DNA2/NAM7 helicase-like, AAA domain;DNA2/NAM7 helicase,... 0.06 OF
SPAC6G9.10c.1 No alias ATP-dependent 5' to 3' DNA/RNA helicase Sen1... 0.13 OF
SPBC29A10.10c.1 No alias tRNA-splicing endonuclease positive effector Dbl8... 0.19 OF

Type GO Term Name Evidence Source

No GO annotation available for this sequence
Toggle parental
Type GO Term Name Evidence Source

No Predicted GO terms available for this sequence
InterPro domains Description Start Stop
IPR041677 DNA2/NAM7_AAA_11 1334 1626
IPR024481 Helicase_Sen1_N 106 859
IPR041679 DNA2/NAM7-like_AAA 1634 1831
No external refs found!