YLR422W


Description : Dock family protein (Dedicator Of CytoKinesis), homolog of human DOCK1; upstream component for regulation through the small GTPase Rho5p; may form a complex with Lmo1p that acts as a GEF for Rho5p; interacts with Ino4p; cytoplasmic protein that relocates to mitochondria under oxidative stress; implicated in mitophagy; not an essential protein; DOCK proteins act as guanine nucleotide exchange factors [Source:SGD;Acc:S000004414]


Gene families : OG_03_0001299 (OF) Phylogenetic Tree(s): OG0001299_tree

Sequence : coding (download), protein (download)


Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood HRR: YLR422W
Cluster HCCA: Cluster_12

Target Alias Description ECC score Gene Family Method Actions
AFR96973 No alias cytoplasmic protein;C2 domain in Dock180 and Zizimin... 0.1 OF
AGV14595 No alias cytoplasmic protein;C2 domain in Dock180 and Zizimin... 0.1 OF
AOA67715 No alias Dedicator of cytokinesis, N-terminal domain 0.13 OF
CAK43684 No alias Dock homology region 2 0.04 OF
EAL88144 No alias SH3 and Ded_cyto domain protein, putative 0.17 OF
EAU91370 No alias cytoplasmic protein 0.06 OF
EED77402 No alias Dedicator of cytokinesis, N-terminal domain 0.02 OF
EGR48611 No alias Dedicator of cytokinesis, C-terminal 0.03 OF
EJF57732 No alias Dock homology region 2 0.09 OF
ESA43744 No alias Dedicator of cytokinesis, C-terminal 0.04 OF
ESA43745 No alias Dedicator of cytokinesis, C-terminal 0.04 OF
ESA43746 No alias Dedicator of cytokinesis, C-terminal 0.04 OF
ESU12059 No alias Dedicator of cytokinesis, C-terminal 0.12 OF
KHC81456 No alias hypothetical protein;Dock homology region 2 0.04 OF
KHC81457 No alias hypothetical protein;DOCK N-terminus;Dock homology region 2 0.03 OF
MGG_03275T0 No alias Putative uncharacterized protein... 0.08 OF
POW15480 No alias DHR-1 domain;E3 ubiquitin ligase, domain of unknown... 0.04 OF

Type GO Term Name Evidence Source

No GO annotation available for this sequence

Type GO Term Name Evidence Source

No Predicted GO terms available for this sequence

InterPro domains Description Start Stop
IPR010703 DOCK_C 1478 1817
No external refs found!