Description : Dock family protein (Dedicator Of CytoKinesis), homolog of human DOCK1; upstream component for regulation through the small GTPase Rho5p; may form a complex with Lmo1p that acts as a GEF for Rho5p; interacts with Ino4p; cytoplasmic protein that relocates to mitochondria under oxidative stress; implicated in mitophagy; not an essential protein; DOCK proteins act as guanine nucleotide exchange factors [Source:SGD;Acc:S000004414]
Gene families : OG_03_0001299 (OF) Phylogenetic Tree(s): OG0001299_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
Type | Description | Actions |
---|---|---|
Neighborhood | HRR: YLR422W | |
Cluster | HCCA: Cluster_12 |
Target | Alias | Description | ECC score | Gene Family Method | Actions |
---|---|---|---|---|---|
AFR96973 | No alias | cytoplasmic protein;C2 domain in Dock180 and Zizimin... | 0.1 | OF | |
AGV14595 | No alias | cytoplasmic protein;C2 domain in Dock180 and Zizimin... | 0.1 | OF | |
AOA67715 | No alias | Dedicator of cytokinesis, N-terminal domain | 0.13 | OF | |
CAK43684 | No alias | Dock homology region 2 | 0.04 | OF | |
EAL88144 | No alias | SH3 and Ded_cyto domain protein, putative | 0.17 | OF | |
EAU91370 | No alias | cytoplasmic protein | 0.06 | OF | |
EED77402 | No alias | Dedicator of cytokinesis, N-terminal domain | 0.02 | OF | |
EGR48611 | No alias | Dedicator of cytokinesis, C-terminal | 0.03 | OF | |
EJF57732 | No alias | Dock homology region 2 | 0.09 | OF | |
ESA43744 | No alias | Dedicator of cytokinesis, C-terminal | 0.04 | OF | |
ESA43745 | No alias | Dedicator of cytokinesis, C-terminal | 0.04 | OF | |
ESA43746 | No alias | Dedicator of cytokinesis, C-terminal | 0.04 | OF | |
ESU12059 | No alias | Dedicator of cytokinesis, C-terminal | 0.12 | OF | |
KHC81456 | No alias | hypothetical protein;Dock homology region 2 | 0.04 | OF | |
KHC81457 | No alias | hypothetical protein;DOCK N-terminus;Dock homology region 2 | 0.03 | OF | |
MGG_03275T0 | No alias | Putative uncharacterized protein... | 0.08 | OF | |
POW15480 | No alias | DHR-1 domain;E3 ubiquitin ligase, domain of unknown... | 0.04 | OF |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
No GO annotation available for this sequence |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
No Predicted GO terms available for this sequence |
InterPro domains | Description | Start | Stop |
---|---|---|---|
IPR010703 | DOCK_C | 1478 | 1817 |
No external refs found! |