YLR401C

Description : Dihydrouridine synthase; member of a widespread family of conserved proteins including Smm1p, Dus1p, and Dus4p; contains a consensus oleate response element (ORE) in its promoter region; forms nuclear foci upon DNA replication stress [Source:SGD;Acc:S000004393]

Gene families : OG_03_0002517 (OF) Phylogenetic Tree(s): OG0002517_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: YLR401C
Cluster	HCCA: Cluster_16

Target	Alias	Description	ECC score	Gene Family Method
AFR97268	No alias	tRNA-dihydrouridine synthase 3;Dihydrouridine synthase (Dus)	0.21	OF
CAG80010	No alias	tRNA-dihydrouridine synthase	0.35	OF
CAK37330	No alias	Dihydrouridine synthase (Dus)	0.04	OF
CBF88723	No alias	tRNA-dihydrouridine synthase 3	0.09	OF
EAA35786	No alias	tRNA-dihydrouridine synthase	0.03	OF
EAL90808	No alias	tRNA dihydrouridine synthase, putative	0.33	OF
EDO03384	No alias	tRNA-dihydrouridine synthase	0.1	OF
EGR47300	No alias	tRNA-dihydrouridine synthase	0.03	OF
MGG_01205T0	No alias	tRNA-dihydrouridine synthase 3...	0.03	OF
SPAC16.04.1	No alias	tRNA dihydrouridine synthase Dus3 (predicted)...	0.06	OF

Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	None	Extended
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0005488	binding	None	Extended
BP	GO:0006139	nucleobase-containing compound metabolic process	None	Extended
BP	GO:0006396	RNA processing	None	Extended
BP	GO:0006399	tRNA metabolic process	None	Extended
BP	GO:0006725	cellular aromatic compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0008033	tRNA processing	IEA	Interproscan
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
BP	GO:0016070	RNA metabolic process	None	Extended
MF	GO:0016491	oxidoreductase activity	None	Extended
MF	GO:0016627	oxidoreductase activity, acting on the CH-CH group of donors	None	Extended
MF	GO:0017150	tRNA dihydrouridine synthase activity	IEA	Interproscan
BP	GO:0034470	ncRNA processing	None	Extended
BP	GO:0034641	cellular nitrogen compound metabolic process	None	Extended
BP	GO:0034660	ncRNA metabolic process	None	Extended
MF	GO:0036094	small molecule binding	None	Extended
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043168	anion binding	None	Extended
BP	GO:0043170	macromolecule metabolic process	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0046483	heterocycle metabolic process	None	Extended
MF	GO:0048037	cofactor binding	None	Extended
MF	GO:0050660	flavin adenine dinucleotide binding	IEA	Interproscan
MF	GO:0050662	coenzyme binding	None	Extended
BP	GO:0055114	oxidation-reduction process	IEA	Interproscan
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:0090304	nucleic acid metabolic process	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:0140098	catalytic activity, acting on RNA	None	Extended
MF	GO:0140101	catalytic activity, acting on a tRNA	None	Extended
MF	GO:1901265	nucleoside phosphate binding	None	Extended
BP	GO:1901360	organic cyclic compound metabolic process	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended

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Type	GO Term	Name	Evidence	Source
No Predicted GO terms available for this sequence

InterPro domains	Description	Start	Stop
IPR001269	tRNA_hU_synthase	501	575
IPR001269	tRNA_hU_synthase	297	481

External Links

No external refs found!

YLR401C

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation