Description : Beta subunit of the translation initiation factor eIF2B; the guanine-nucleotide exchange factor for eIF2; activity subsequently regulated by phosphorylated eIF2; first identified as a negative regulator of GCN4 expression; human homolog EIF2B2 can complement yeast mutant, allows growth down-regulation of yeast gene [Source:SGD;Acc:S000004282]
Gene families : OG_03_0002858 (OF) Phylogenetic Tree(s): OG0002858_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
Type | Description | Actions |
---|---|---|
Neighborhood | HRR: YLR291C | |
Cluster | HCCA: Cluster_92 |
Target | Alias | Description | ECC score | Gene Family Method | Actions |
---|---|---|---|---|---|
CAG78635 | No alias | Initiation factor 2B-related | 0.04 | OF | |
CAK45250 | No alias | Initiation factor 2 subunit family | 0.05 | OF | |
EAA31440 | No alias | Initiation factor 2B-related | 0.09 | OF | |
EAL90274 | No alias | translation regulator GCD7 | 0.06 | OF | |
EAU88779 | No alias | eukaryotic translation initiation factor 2B subunit 2 | 0.02 | OF | |
EGR44391 | No alias | Initiation factor 2B-related | 0.03 | OF | |
ESU16999 | No alias | Initiation factor 2B-related | 0.11 | OF | |
SPAC343.14c.1 | No alias | translation initiation factor eIF2B beta subunit... | 0.03 | OF |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
BP | GO:0044237 | cellular metabolic process | IEA | Interproscan |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
No Predicted GO terms available for this sequence |
InterPro domains | Description | Start | Stop |
---|---|---|---|
IPR000649 | IF-2B-related | 33 | 358 |
No external refs found! |