YLR186W


Description : Methyltransferase for rRNA; methylates pseudouridine 18S rRNA residue 1191; member of the SPOUT methyltransferase family; required for maturation of 18S rRNA and for 40S ribosomal subunit production independent of methyltransferase activity; forms homodimers; human ortholog is mutated in Bowen-Conradi syndrome, and equivalent yeast mutation affects Emg1p dimerization and localization but not methyltransferase activity; human EMG1 complements lethality of null and ts mutant [Source:SGD;Acc:S000004176]


Gene families : OG_03_0002302 (OF) Phylogenetic Tree(s): OG0002302_tree

Sequence : coding (download), protein (download)


Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood HRR: YLR186W
Cluster HCCA: Cluster_69

Target Alias Description ECC score Gene Family Method Actions
AFR97447 No alias nucleolar essential protein 1;EMG1/NEP1 methyltransferase 0.12 OF
AOA66426 No alias Ribosomal biogenesis, methyltransferase, EMG1/NEP1 0.02 OF
CAG78997 No alias Ribosomal biogenesis, methyltransferase, EMG1/NEP1 0.06 OF
ESU16489 No alias nucleolar essential protein 1 0.03 OF
KHC83880 No alias ribosomal RNA small subunit methyltransferase... 0.06 OF
SPAC18G6.07c.1 No alias rRNA (pseudouridine) methyltransferase Mra1... 0.11 OF

Type GO Term Name Evidence Source
MF GO:0008168 methyltransferase activity IEA Interproscan
Type GO Term Name Evidence Source

No Predicted GO terms available for this sequence

InterPro domains Description Start Stop
IPR005304 Rbsml_bgen_MeTrfase_EMG1/NEP1 43 246
No external refs found!