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  5. YBR136W

YBR136W


Description : Genome integrity checkpoint protein and PI kinase superfamily member; Mec1p and Dun1p function in same pathway to regulate dNTP pools and telomere length; signal transducer required for cell cycle arrest and transcriptional responses to damaged or unreplicated DNA; facilitates replication fork progression and regulates P-body formation under replication stress; promotes interhomolog recombination by phosphorylating Hop1p; associates with shortened, dysfunctional telomeres [Source:SGD;Acc:S000000340]


Gene families : OG_03_0002163 (OF) Phylogenetic Tree(s): OG0002163_tree

Sequence : coding (download), protein (download)


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Type Description Actions
Neighborhood HRR: YBR136W
Cluster HCCA: Cluster_12

Target Alias Description ECC score Gene Family Method Actions
AFR95585 No alias serine/threonine-protein kinase ATR;FAT domain;FATC... 0.11 OF
AOA67853 No alias PIK-related kinase, FAT 0.12 OF
CAG78481 No alias PIK-related kinase, FAT 0.13 OF
CBF79340 No alias UVSB 0.12 OF
EAL84624 No alias inositol kinase kinase (UvsB), putative 0.03 OF
EAU84196 No alias atypical/PIKK/ATR protein kinase 0.04 OF
EDO65367 No alias FATC domain 0.02 OF
EED44846 No alias inositol kinase kinase (UvsB), putative 0.02 OF
EGR46540 No alias Phosphatidylinositol 3-/4-kinase, catalytic domain 0.07 OF
EJF62344 No alias Phosphatidylinositol 3- and 4-kinase 0.04 OF
ESU14630 No alias PIK-related kinase, FAT 0.03 OF
KHC75297 No alias serine/threonine-protein kinase... 0.34 OF
MGG_02656T0 No alias Protein kinase rad3 [Source:UniProtKB/TrEMBL;Acc:G4NJG7] 0.02 OF
POW12614 No alias UME domain;Phosphatidylinositol 3-/4-kinase, catalytic... 0.08 OF
SPBC216.05.1 No alias ATR checkpoint kinase Rad3 [Source:PomBase;Acc:SPBC216.05] 0.26 OF

Type GO Term Name Evidence Source
MF GO:0004674 protein serine/threonine kinase activity IEA Interproscan
MF GO:0005515 protein binding IEA Interproscan
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Type GO Term Name Evidence Source

No Predicted GO terms available for this sequence
InterPro domains Description Start Stop
IPR012993 UME 876 977
IPR003152 FATC_dom 2338 2368
IPR003151 PIK-rel_kinase_FAT 1572 1853
IPR000403 PI3/4_kinase_cat_dom 2076 2314
No external refs found!