YLR056W


Description : C-5 sterol desaturase; glycoprotein that catalyzes the introduction of a C-5(6) double bond into episterol, a precursor in ergosterol biosynthesis; transcriptionally down-regulated when ergosterol is in excess; mutants are viable, but cannot grow on non-fermentable carbon sources; substrate of HRD ubiquitin ligase; mutation is functionally complemented by human SC5D [Source:SGD;Acc:S000004046]


Gene families : OG_03_0000856 (OF) Phylogenetic Tree(s): OG0000856_tree

Sequence : coding (download), protein (download)


Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood HRR: YLR056W
Cluster HCCA: Cluster_17

Target Alias Description ECC score Gene Family Method Actions
AFR92650 No alias lathosterol oxidase;Fatty acid hydroxylase superfamily 0.12 OF
AOA65845 No alias Fatty acid hydroxylase 0.02 OF
CAK42184 No alias Fatty acid hydroxylase superfamily 0.04 OF
CAK48602 No alias Fatty acid hydroxylase superfamily 0.04 OF
CBF70874 No alias sterol delta 5,6-desaturase ERG3 0.09 OF
CBF75720 No alias conserved hypothetical protein 0.02 OF
EAA29014 No alias Fatty acid hydroxylase 0.04 OF
EAA33687 No alias Fatty acid hydroxylase 0.05 OF
EAL85061 No alias sterol desaturase, putative 0.03 OF
EAL85525 No alias sterol delta 5,6-desaturase ERG3 0.06 OF
EAL87130 No alias sterol delta 5,6-desaturase, putative 0.07 OF
EAU85433 No alias fatty acid hydroxylase 0.12 OF
ESU10897 No alias Fatty acid hydroxylase 0.1 OF
KHC83255 No alias C-5 sterol desaturase;Fatty acid hydroxylase superfamily 0.16 OF
SPAC1687.16c.1 No alias C-5 sterol desaturase Erg31 [Source:PomBase;Acc:SPAC1687.16c] 0.04 OF

Type GO Term Name Evidence Source
MF GO:0005506 iron ion binding IEA Interproscan
BP GO:0008610 lipid biosynthetic process IEA Interproscan
MF GO:0016491 oxidoreductase activity IEA Interproscan
BP GO:0055114 oxidation-reduction process IEA Interproscan
Type GO Term Name Evidence Source

No Predicted GO terms available for this sequence

InterPro domains Description Start Stop
IPR006694 Fatty_acid_hydroxylase 187 311
No external refs found!