YLR028C


Description : Enzyme of 'de novo' purine biosynthesis; contains both 5-aminoimidazole-4-carboxamide ribonucleotide transformylase and inosine monophosphate cyclohydrolase activities; ADE16 has a paralog, ADE17, that arose from the whole genome duplication; ade16 ade17 mutants require adenine and histidine [Source:SGD;Acc:S000004018]


Gene families : OG_03_0001895 (OF) Phylogenetic Tree(s): OG0001895_tree

Sequence : coding (download), protein (download)


Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood HRR: YLR028C
Cluster HCCA: Cluster_46

Target Alias Description ECC score Gene Family Method Actions
CAG81431 No alias Methylglyoxal synthase-like domain 0.03 OF
ESU06226 No alias bifunctional purine biosynthesis protein ADE17 0.02 OF

Type GO Term Name Evidence Source
MF GO:0003937 IMP cyclohydrolase activity IEA Interproscan
MF GO:0004643 phosphoribosylaminoimidazolecarboxamide formyltransferase activity IEA Interproscan
BP GO:0006164 purine nucleotide biosynthetic process IEA Interproscan
Type GO Term Name Evidence Source

No Predicted GO terms available for this sequence

InterPro domains Description Start Stop
IPR011607 MGS-like_dom 17 131
IPR002695 PurH-like 136 460
No external refs found!