YLL026W


Description : Disaggregase; heat shock protein that cooperates with Ydj1p (Hsp40) and Ssa1p (Hsp70) to refold and reactivate previously denatured, aggregated proteins; responsive to stresses including: heat, ethanol, and sodium arsenite; involved in [PSI+] propagation; protein becomes more abundant and forms cytoplasmic foci in response to DNA replication stress; potentiated Hsp104p variants decrease TDP-43 proteotoxicity by eliminating its cytoplasmic aggregation [Source:SGD;Acc:S000003949]


Gene families : OG_03_0000415 (OF) Phylogenetic Tree(s): OG0000415_tree

Sequence : coding (download), protein (download)


Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood HRR: YLL026W
Cluster HCCA: Cluster_30

Target Alias Description ECC score Gene Family Method Actions
AFR92430 No alias heat shock protein;C-terminal, D2-small domain, of ClpB... 0.22 OF
AFR96568 No alias ATP-dependent Clp protease ATP-binding subunit... 0.15 OF
AOA66285 No alias ClpA/ClpB, AAA lid domain 0.25 OF
AOA67116 No alias Clp ATPase, C-terminal 0.12 OF
CAG78137 No alias ATPase, AAA-type, core 0.12 OF
CAG80093 No alias ClpA/ClpB, AAA lid domain 0.16 OF
CAK45384 No alias C-terminal, D2-small domain, of ClpB protein 0.08 OF
CAK96205 No alias C-terminal, D2-small domain, of ClpB protein 0.03 OF
CBF88019 No alias oligomeric mitochondrial matrix chaperone 0.15 OF
CBF88645 No alias heat shock protein 0.16 OF
EAA27992 No alias Clp, N-terminal 0.17 OF
EAA34819 No alias ATPase, AAA-type, core 0.14 OF
EAL90445 No alias heat shock protein/chaperonin HSP78, putative 0.11 OF
EAL90858 No alias heat shock protein Hsp98/Hsp104/ClpA, putative 0.12 OF
EAU93105 No alias No description available 0.07 OF
EDN97704 No alias ATPase, AAA-type, core 0.03 OF
EFI27311 No alias hsp78-like protein 0.07 OF
EGR46636 No alias ATPase, AAA-type, core 0.08 OF
EGR51514 No alias ATPase, AAA-type, core 0.04 OF
ESU06283 No alias heat shock protein 78 0.08 OF
ESU11446 No alias heat shock protein HSP98 0.08 OF
KHC70684 No alias hypothetical protein;AAA lid domain;"C-terminal,... 0.16 OF
KHC81399 No alias hsp78-like protein;AAA lid domain;AAA domain (Cdc48... 0.14 OF
MGG_04437T0 No alias Heat shock protein 78 [Source:UniProtKB/TrEMBL;Acc:G4MSB3] 0.11 OF
MGG_06459T0 No alias Hsp98-like protein [Source:UniProtKB/TrEMBL;Acc:G4N778] 0.06 OF
POW00387 No alias ATPase, AAA-type, core;ATPase, AAA-type, core;ClpA/ClpB,... 0.12 OF
POW06771 No alias ATPase, AAA-type, core 0.12 OF
SPBC16D10.08c.1 No alias heat shock protein Hsp104 (predicted)... 0.21 OF
SPBC4F6.17c.1 No alias mitochondrial heatshock protein Hsp78 (predicted)... 0.24 OF

Type GO Term Name Evidence Source
MF GO:0005524 ATP binding IEA Interproscan
Type GO Term Name Evidence Source

No Predicted GO terms available for this sequence

InterPro domains Description Start Stop
IPR004176 Clp_N 18 43
IPR004176 Clp_N 99 149
IPR019489 Clp_ATPase_C 775 857
IPR003959 ATPase_AAA_core 209 326
IPR041546 ClpA/ClpB_AAA_lid 344 440
IPR003959 ATPase_AAA_core 607 768
No external refs found!