YKR080W

Description : NAD-dependent 5,10-methylenetetrahydrafolate dehydrogenase; plays a catalytic role in oxidation of cytoplasmic one-carbon units; expression is regulated by Bas1p and Bas2p, repressed by adenine, and may be induced by inositol and choline [Source:SGD;Acc:S000001788]

Gene families : OG_03_0002388 (OF) Phylogenetic Tree(s): OG0002388_tree

Sequence : coding (download), protein (download)

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Type	Description	Actions
Neighborhood	HRR: YKR080W
Cluster	HCCA: Cluster_7

Target	Alias	Description	ECC score	Gene Family Method
AOA65798	No alias	Tetrahydrofolate dehydrogenase/cyclohydrolase,...	0.18	OF
CAL00513	No alias	Tetrahydrofolate dehydrogenase/cyclohydrolase,...	0.03	OF
CBF85042	No alias	methylenetetrahydrofolate dehydrogenase	0.02	OF
EAL85297	No alias	methylenetetrahydrofolate dehydrogenase	0.04	OF
EAU84432	No alias	methylenetetrahydrofolate dehydrogenase	0.04	OF
EGR50970	No alias	Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain	0.03	OF
ESA44211	No alias	Tetrahydrofolate dehydrogenase/cyclohydrolase,...	0.02	OF
ESA44212	No alias	Tetrahydrofolate dehydrogenase/cyclohydrolase,...	0.02	OF
ESU05598	No alias	methylenetetrahydrofolate dehydrogenase	0.1	OF
KHC76560	No alias	methylenetetrahydrofolate dehydrogenase...	0.24	OF
SPBC1711.04.1	No alias	methylenetetrahydrofolate reductase Mtd1 (predicted)...	0.04	OF

Type	GO Term	Name	Evidence	Source
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0004486	methylenetetrahydrofolate dehydrogenase [NAD(P)+] activity	None	Extended
MF	GO:0004488	methylenetetrahydrofolate dehydrogenase (NADP+) activity	IEA	Interproscan
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
MF	GO:0016491	oxidoreductase activity	None	Extended
MF	GO:0016645	oxidoreductase activity, acting on the CH-NH group of donors	None	Extended
MF	GO:0016646	oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor	None	Extended
BP	GO:0055114	oxidation-reduction process	IEA	Interproscan

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Type	GO Term	Name	Evidence	Source
No Predicted GO terms available for this sequence

InterPro domains	Description	Start	Stop
IPR020630	THF_DH/CycHdrlase_cat_dom	8	121
IPR020631	THF_DH/CycHdrlase_NAD-bd_dom	144	209

External Links

No external refs found!

YKR080W

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation