Description : Import and assembly protein in mitochondrial intermembrane space; component of MIA pathway which mediates import and oxidative folding of substrates including small proteins containing twin cysteine motifs; acts in concert with Erv1p, which oxidizes the cysteine residues of Mia40p to comprise a disulfide relay system that catalyzes import; also mediates folding of Atp23p via a chaperone-like activity; forms a dimer that binds iron-sulfur cluster in vitro [Source:SGD;Acc:S000001678]
Gene families : OG_03_0000920 (OF) Phylogenetic Tree(s): OG0000920_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
Type | Description | Actions |
---|---|---|
Neighborhood | HRR: YKL195W | |
Cluster | HCCA: Cluster_27 |
Target | Alias | Description | ECC score | Gene Family Method | Actions |
---|---|---|---|---|---|
AFR95713 | No alias | mitochondrial intermembrane space import and assembly... | 0.03 | OF | |
AOA67642 | No alias | CHCH domain | 0.05 | OF | |
CAG79822 | No alias | CHCH | 0.09 | OF | |
CAK39365 | No alias | CHCH domain | 0.03 | OF | |
EAA30157 | No alias | CHCH | 0.2 | OF | |
EAL86929 | No alias | mitochondrial intermembrane space protein Mia40 | 0.05 | OF | |
EAU91393 | No alias | intermembrane space import and assembly protein 40 | 0.11 | OF | |
EDO01158 | No alias | CHCH | 0.03 | OF | |
EJF58235 | No alias | CHCH domain | 0.02 | OF | |
ESU07892 | No alias | hypothetical protein | 0.04 | OF | |
KHC83069 | No alias | mitochondrial intermembrane space import and assembly... | 0.04 | OF | |
MGG_09348T0 | No alias | Mitochondrial intermembrane space import and assembly... | 0.1 | OF | |
POW17053 | No alias | CHCH | 0.02 | OF |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
No GO annotation available for this sequence |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
No Predicted GO terms available for this sequence |
InterPro domains | Description | Start | Stop |
---|---|---|---|
IPR010625 | CHCH | 307 | 343 |
No external refs found! |