Description : Widely-conserved NADHX dehydratase; converts (S)-NADHX to NADH in ATP-dependent manner; YKL151C promoter contains STREs (stress response elements) and expression is induced by heat shock or methyl methanesulfonate; downstream intergenic region drives antisense expression and mediates coordinated regulation of YKL151C and GPM1 phosphoglycerate mutase; protein abundance increases in response to DNA replication stress; homolog of Carkd in mammals and C-terminus of YjeF in E.coli [Source:SGD;Acc:S000001634]
Gene families : OG_03_0001870 (OF) Phylogenetic Tree(s): OG0001870_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
Type | Description | Actions |
---|---|---|
Neighborhood | HRR: YKL151C | |
Cluster | HCCA: Cluster_64 |
Target | Alias | Description | ECC score | Gene Family Method | Actions |
---|---|---|---|---|---|
AFR94362 | No alias | YjeF family protein;Carbohydrate kinase | 0.05 | OF | |
AOA70330 | No alias | ATP-dependent (S)-NAD(P)H-hydrate dehydratase | 0.03 | OF | |
CAG80881 | No alias | ATP-dependent (S)-NAD(P)H-hydrate dehydratase | 0.07 | OF | |
CAK42918 | No alias | Carbohydrate kinase | 0.02 | OF | |
CBF70399 | No alias | YjeF domain protein | 0.06 | OF | |
EAA36408 | No alias | ATP-dependent (S)-NAD(P)H-hydrate dehydratase | 0.03 | OF | |
EAL93307 | No alias | YjeF domain protein | 0.05 | OF | |
EAU90481 | No alias | YjeF domain-containing protein | 0.03 | OF | |
EDN96760 | No alias | ATP-dependent (S)-NAD(P)H-hydrate dehydratase | 0.02 | OF | |
EGR51547 | No alias | ATP-dependent (S)-NAD(P)H-hydrate dehydratase | 0.03 | OF | |
KHC73344 | No alias | YjeF family domain-containing protein;Carbohydrate kinase | 0.1 | OF | |
SPCC61.03.1 | No alias | NADHX dehydratase (predicted) [Source:PomBase;Acc:SPCC61.03] | 0.04 | OF |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
MF | GO:0052855 | ADP-dependent NAD(P)H-hydrate dehydratase activity | IEA | Interproscan |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
No Predicted GO terms available for this sequence |
InterPro domains | Description | Start | Stop |
---|---|---|---|
IPR000631 | CARKD | 35 | 305 |
No external refs found! |