Description : Widely-conserved NADHX dehydratase; converts (S)-NADHX to NADH in ATP-dependent manner; YKL151C promoter contains STREs (stress response elements) and expression is induced by heat shock or methyl methanesulfonate; downstream intergenic region drives antisense expression and mediates coordinated regulation of YKL151C and GPM1 phosphoglycerate mutase; protein abundance increases in response to DNA replication stress; homolog of Carkd in mammals and C-terminus of YjeF in E.coli [Source:SGD;Acc:S000001634]

Gene families : OG_03_0001870 (OF) Phylogenetic Tree(s): OG0001870_tree

Sequence : coding (download), protein (download)

Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type Description Actions
Neighborhood HRR: YKL151C
Cluster HCCA: Cluster_64

Target Alias Description ECC score Gene Family Method Actions
AFR94362 No alias YjeF family protein;Carbohydrate kinase 0.05 OF
AOA70330 No alias ATP-dependent (S)-NAD(P)H-hydrate dehydratase 0.03 OF
CAG80881 No alias ATP-dependent (S)-NAD(P)H-hydrate dehydratase 0.07 OF
CAK42918 No alias Carbohydrate kinase 0.02 OF
CBF70399 No alias YjeF domain protein 0.06 OF
EAA36408 No alias ATP-dependent (S)-NAD(P)H-hydrate dehydratase 0.03 OF
EAL93307 No alias YjeF domain protein 0.05 OF
EAU90481 No alias YjeF domain-containing protein 0.03 OF
EDN96760 No alias ATP-dependent (S)-NAD(P)H-hydrate dehydratase 0.02 OF
EGR51547 No alias ATP-dependent (S)-NAD(P)H-hydrate dehydratase 0.03 OF
KHC73344 No alias YjeF family domain-containing protein;Carbohydrate kinase 0.1 OF
SPCC61.03.1 No alias NADHX dehydratase (predicted) [Source:PomBase;Acc:SPCC61.03] 0.04 OF

Type GO Term Name Evidence Source
MF GO:0052855 ADP-dependent NAD(P)H-hydrate dehydratase activity IEA Interproscan
Type GO Term Name Evidence Source

No Predicted GO terms available for this sequence

InterPro domains Description Start Stop
IPR000631 CARKD 35 305
No external refs found!