Description : Flavoprotein subunit of succinate dehydrogenase; couples the oxidation of succinate to the transfer of electrons to ubiquinone as part of the TCA cycle and the mitochondrial respiratory chain; FAD binding to Sdh1p is required for the assembly of the succinate dehydrogenase subunits; mutations in human ortholog SDHA are associated with Leigh syndrome [Source:SGD;Acc:S000001631]
Gene families : OG_03_0001471 (OF) Phylogenetic Tree(s): OG0001471_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
Type | Description | Actions |
---|---|---|
Neighborhood | HRR: YKL148C | |
Cluster | HCCA: Cluster_31 |
Target | Alias | Description | ECC score | Gene Family Method | Actions |
---|---|---|---|---|---|
AFR96921 | No alias | succinate dehydrogenase [ubiquinone] flavoprotein... | 0.07 | OF | |
AOA69620 | No alias | FAD-dependent oxidoreductase 2, FAD binding domain | 0.11 | OF | |
CAG80884 | No alias | Fumarate reductase/succinate dehydrogenase... | 0.1 | OF | |
CAK44547 | No alias | Fumarate reductase flavoprotein C-term | 0.1 | OF | |
CBF83753 | No alias | hypothetical protein similar to succinate dehydrogenase... | 0.11 | OF | |
EAL92794 | No alias | succinate dehydrogenase subunit Sdh1, putative | 0.15 | OF | |
EAU81873 | No alias | succinate dehydrogenase flavoprotein subunit | 0.11 | OF | |
EDO65095 | No alias | FAD-dependent oxidoreductase 2, FAD binding domain | 0.07 | OF | |
EGR50212 | No alias | FAD-dependent oxidoreductase 2, FAD binding domain | 0.02 | OF | |
ESU13615 | No alias | succinate dehydrogenase flavoprotein subunit | 0.09 | OF | |
KHC76732 | No alias | succinate dehydrogenase [ubiquinone] flavoprotein... | 0.26 | OF | |
MGG_00168T0 | No alias | Putative uncharacterized protein... | 0.01 | OF | |
POW00414 | No alias | Fumarate reductase/succinate dehydrogenase... | 0.03 | OF | |
SPAC1556.02c.1 | No alias | succinate dehydrogenase Sdh1 (predicted)... | 0.2 | OF |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
MF | GO:0016491 | oxidoreductase activity | IEA | Interproscan |
BP | GO:0055114 | oxidation-reduction process | IEA | Interproscan |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
No Predicted GO terms available for this sequence |
No external refs found! |