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  5. YKL126W

YKL126W


Description : S/T protein kinase; phosphorylates, downregulates flippase activator Fpk1p; inactivates Orm1p and Orm2p by phosphorylation in response to compromised sphingolipid synthesis; involved in the TORC-dependent phosphorylation of ribosomal proteins Rps6a/b (S6); mutations affect receptor-mediated endocytosis and sphingolipid-mediated and cell integrity signaling pathways; human homolog SGK1 can complement a null mutant; human homolog SGK2 can complement a ypk1 ypk2 double mutant [Source:SGD;Acc:S000001609]


Gene families : OG_03_0000360 (OF) Phylogenetic Tree(s): OG0000360_tree

Sequence : coding (download), protein (download)


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Type Description Actions
Neighborhood HRR: YKL126W
Cluster HCCA: Cluster_34

Target Alias Description ECC score Gene Family Method Actions
AFR97540 No alias AGC/Akt protein kinase;Haspin like kinase domain;Protein... 0.02 OF
CBF70443 No alias serine/threonine protein kinase 0.02 OF
MGG_01260T0 No alias AGC/RSK/P70 protein kinase [Source:UniProtKB/TrEMBL;Acc:G4MY34] 0.02 OF

Type GO Term Name Evidence Source
MF GO:0004672 protein kinase activity IEA Interproscan
MF GO:0004674 protein serine/threonine kinase activity IEA Interproscan
MF GO:0005524 ATP binding IEA Interproscan
BP GO:0006468 protein phosphorylation IEA Interproscan
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Type GO Term Name Evidence Source

No Predicted GO terms available for this sequence
InterPro domains Description Start Stop
IPR000719 Prot_kinase_dom 349 602
IPR017892 Pkinase_C 623 663
No external refs found!