YKL100C


Description : Intramembrane aspartyl protease of the perinuclear ER membrane; acts in a branch of ER-associated degradation (ERAD) that degrades functional proteins rather than misfolded proteins; regulates abundance of high-affinity plasma membrane transporters, such as Ctr1p and Zrt1p, during the starvation response; has a presenilin fold; member of the GxGD family of intramembrane proteases; closest human homolog is signal peptide peptidase (SPP) [Source:SGD;Acc:S000001583]


Gene families : OG_03_0004656 (OF) Phylogenetic Tree(s): OG0004656_tree

Sequence : coding (download), protein (download)


Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood HRR: YKL100C
Cluster HCCA: Cluster_46

Target Alias Description ECC score Gene Family Method Actions
EAL85824 No alias signal peptide peptidase, putative 0.02 OF

Type GO Term Name Evidence Source
MF GO:0004190 aspartic-type endopeptidase activity IEA Interproscan
CC GO:0016021 integral component of membrane IEA Interproscan
Type GO Term Name Evidence Source

No Predicted GO terms available for this sequence

InterPro domains Description Start Stop
IPR007369 Peptidase_A22B_SPP 145 509
No external refs found!