Description : Subunit of both the ERMES and the SAM complex; component of ERMES complex which acts as a molecular tether between the mitochondria and the ER, necessary for efficient phospholipid exchange between organelles and for mitophagy; SAM/TOB complex component that functions in the assembly of outer membrane beta-barrel proteins; involved in mitochondrial inheritance and morphology; ERMES complex is often co-localized with peroxisomes and concentrated areas of pyruvate dehydrogenase [Source:SGD;Acc:S000000008]
Gene families : OG_03_0001999 (OF) Phylogenetic Tree(s): OG0001999_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
Type | Description | Actions |
---|---|---|
Neighborhood | HRR: YAL010C | |
Cluster | HCCA: Cluster_23 |
Target | Alias | Description | ECC score | Gene Family Method | Actions |
---|---|---|---|---|---|
AOA66003 | No alias | Mitochondrial distribution and morphology protein 10 | 0.03 | OF | |
KHC81532 | No alias | mitochondrial distribution and morphology protein... | 0.05 | OF |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
BP | GO:0007005 | mitochondrion organization | IEA | Interproscan |
CC | GO:0032865 | ERMES complex | IEA | Interproscan |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
No Predicted GO terms available for this sequence |
InterPro domains | Description | Start | Stop |
---|---|---|---|
IPR027539 | Mdm10 | 1 | 493 |
No external refs found! |