YJR104C


Description : Cytosolic copper-zinc superoxide dismutase; detoxifies superoxide; stabilizes Yck1p and Yck2p kinases in glucose to repress respiration; phosphorylated by Dun1p, enters nucleus under oxidative stress to promote transcription of stress response genes; human ortholog SOD1 implicated in ALS complements a null allele; abundance increases under DNA replication stress and during exposure to boric acid; localization to mitochondrial intermembrane space is modulated by MICOS complex [Source:SGD;Acc:S000003865]


Gene families : OG_03_0002954 (OF) Phylogenetic Tree(s): OG0002954_tree

Sequence : coding (download), protein (download)


Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood HRR: YJR104C
Cluster HCCA: Cluster_19

Target Alias Description ECC score Gene Family Method Actions
AOA69725 No alias Superoxide dismutase, copper/zinc binding domain 0.06 OF
CAG79443 No alias Superoxide dismutase, copper/zinc binding domain 0.05 OF
CBF89897 No alias Superoxide dismutase [Cu-Zn] 0.04 OF
EAA35055 No alias Superoxide dismutase, copper/zinc binding domain 0.03 OF
EDN91296 No alias Superoxide dismutase, copper/zinc binding domain 0.03 OF
ESU14586 No alias superoxide dismutase 0.03 OF
SPAC821.10c.1 No alias superoxide dismutase Sod1 [Source:PomBase;Acc:SPAC821.10c] 0.07 OF

Type GO Term Name Evidence Source
BP GO:0006801 superoxide metabolic process IEA Interproscan
MF GO:0046872 metal ion binding IEA Interproscan
Type GO Term Name Evidence Source

No Predicted GO terms available for this sequence

InterPro domains Description Start Stop
IPR001424 SOD_Cu_Zn_dom 12 150
No external refs found!