Description : CDK inhibitor and nuclear anchor; during the cell cycle Far1p sequesters the GEF Cdc24p in the nucleus; phosphorylation by Cdc28p-Cln results in SCFCdc4 complex-mediated ubiquitin-dependent degradation, releasing Cdc24p for export and activation of GTPase Cdc42p; in response to pheromone, phosphorylation of Far1p by MAPK Fus3p results in association with, and inhibition of Cdc28p-Cln, as well as Msn5p mediated nuclear export of Far1p-Cdc24p, targeting Cdc24p to polarity sites [Source:SGD;Acc:S000003693]
Gene families : OG_03_0002182 (OF) Phylogenetic Tree(s): OG0002182_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
Type | Description | Actions |
---|---|---|
Neighborhood | HRR: YJL157C | |
Cluster | HCCA: Cluster_25 |
Target | Alias | Description | ECC score | Gene Family Method | Actions |
---|---|---|---|---|---|
AFR96278 | No alias | zinc finger family protein;Pleckstrin homology domain | 0.05 | OF | |
AOA65709 | No alias | No description available | 0.05 | OF | |
AOA65716 | No alias | No description available | 0.11 | OF | |
CAK39713 | No alias | No description available | 0.03 | OF | |
CBF81002 | No alias | von Willebrand and RING finger domain protein | 0.04 | OF | |
EAA29374 | No alias | Pleckstrin homology domain | 0.02 | OF | |
EAL88554 | No alias | von Willebrand and RING finger domain protein | 0.03 | OF | |
EED54943 | No alias | von Willebrand and RING finger domain protein | 0.04 | OF | |
KHC71714 | No alias | hypothetical protein | 0.05 | OF | |
POW12899 | No alias | Pleckstrin homology domain | 0.02 | OF |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
No GO annotation available for this sequence |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
No Predicted GO terms available for this sequence |
No InterPro domains available for this sequence
No external refs found! |