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YJL154C


Description : Endosomal subunit of membrane-associated retromer complex; required for retrograde transport; receptor that recognizes retrieval signals on cargo proteins, forms subcomplex with Vps26p and Vps29p that selects cargo proteins for retrieval; interacts with Ypt7p; overexpression of wild-type human VPS35 or Parkinson's-associated vps35-D686N or vps35-P299S variants complements Ni2+ resistance and Cd2+ sensitivity of yeast vps35 null mutant [Source:SGD;Acc:S000003690]


Gene families : OG_03_0003205 (OF) Phylogenetic Tree(s): OG0003205_tree

Sequence : coding (download), protein (download)


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Type Description Actions
Neighborhood HRR: YJL154C
Cluster HCCA: Cluster_56

Target Alias Description ECC score Gene Family Method Actions
AFR98033 No alias vacuolar protein sorting-associated protein... 0.05 OF
AOA66709 No alias Vacuolar protein sorting-associated protein 35 0.04 OF
CAG79655 No alias Vacuolar protein sorting-associated protein 35 0.06 OF
CAK46844 No alias Vacuolar protein sorting-associated protein 35 0.04 OF
CBF76410 No alias vacuolar sorting protein 35 0.04 OF
EAA33310 No alias Vacuolar protein sorting-associated protein 35 0.08 OF
EAL92545 No alias vacuolar sorting protein 35 0.03 OF
EAU93279 No alias vacuolar protein sorting-associated protein 35 0.02 OF
EGR52907 No alias Vacuolar protein sorting-associated protein 35 0.05 OF
EJF58828 No alias Vacuolar protein sorting-associated protein 35 0.03 OF
KHC81606 No alias hypothetical protein;Vacuolar protein sorting-associated... 0.09 OF
MGG_05089T0 No alias Vacuolar protein sorting-associated protein 35... 0.04 OF
POW10606 No alias Vacuolar protein sorting-associated protein 35 0.02 OF
SPCC777.13.1 No alias retromer complex subunit Vps35 [Source:PomBase;Acc:SPCC777.13] 0.06 OF

Type GO Term Name Evidence Source
BP GO:0015031 protein transport IEA Interproscan
CC GO:0030906 retromer, cargo-selective complex IEA Interproscan
BP GO:0042147 retrograde transport, endosome to Golgi IEA Interproscan
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Type GO Term Name Evidence Source

No Predicted GO terms available for this sequence
InterPro domains Description Start Stop
IPR005378 Vps35 8 829
No external refs found!