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  5. YBR061C

YBR061C


Description : 2'-O-ribose methyltransferase; methylates the 2'-O-ribose of tRNA-Phe, tRNA-Trp, and tRNA-Leu at positions C32 and N34 of tRNA anticodon loop; crucial biological role likely modification of tRNA-Phe; interacts with Trm732p and Rtt10p in 2'-O-methylation of C32 and N34 substrate tRNAs, respectively; yeast null mutant can be functionally complemented by human FTSJ1, mutations in which have been implicated in nonsyndromic X-linked intellectual disability (NSXLID) [Source:SGD;Acc:S000000265]


Gene families : OG_03_0000402 (OF) Phylogenetic Tree(s): OG0000402_tree

Sequence : coding (download), protein (download)


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Type Description Actions
Neighborhood HRR: YBR061C
Cluster HCCA: Cluster_69

Target Alias Description ECC score Gene Family Method Actions
AFR93268 No alias AdoMet-dependent rRNA methyltransferase SPB1;Spb1... 0.08 OF
AOA68383 No alias Ribosomal RNA methyltransferase FtsJ domain 0.16 OF
AOA70393 No alias Ribosomal RNA methyltransferase Spb1, domain of unknown... 0.08 OF
CAG78290 No alias Ribosomal RNA methyltransferase FtsJ domain 0.14 OF
CAG80799 No alias Ribosomal RNA methyltransferase, Spb1, C-terminal 0.05 OF
CAK47295 No alias Domain of unknown function (DUF3381) 0.09 OF
CAK96963 No alias FtsJ-like methyltransferase 0.07 OF
CBF85494 No alias tRNA methyltransferase, putative 0.04 OF
CBF90216 No alias AdoMet-dependent rRNA methyltransferase spb1 0.08 OF
EAA28419 No alias Ribosomal RNA methyltransferase FtsJ domain 0.03 OF
EAA32209 No alias Ribosomal RNA methyltransferase FtsJ domain 0.08 OF
EAL88742 No alias tRNA methyltransferase, putative 0.04 OF
EAL91403 No alias rRNA methyltransferase Spb1, putative 0.07 OF
EAU93073 No alias RNA methyltransferase 0.06 OF
EDO00644 No alias Ribosomal RNA methyltransferase, Spb1, C-terminal 0.09 OF
EDO00645 No alias Ribosomal RNA methyltransferase FtsJ domain 0.08 OF
EED48651 No alias tRNA methyltransferase, putative 0.04 OF
EED80435 No alias Ribosomal RNA methyltransferase, Spb1, C-terminal 0.03 OF
EGR45000 No alias Ribosomal RNA methyltransferase, Spb1, C-terminal 0.04 OF
EGR46840 No alias Ribosomal RNA methyltransferase FtsJ domain 0.06 OF
ESU13717 No alias AdoMet-dependent rRNA methyltransferase spb-1 0.07 OF
ESU15855 No alias tRNA (uridine-2'-O-)-methyltransferase TRM7 0.05 OF
KHC73553 No alias AdoMet-dependent rRNA methyltransferase SPB1;FtsJ-like... 0.05 OF
KHC79277 No alias tRNA (uridine-2'-O-)-methyltransferase TRM7;FtsJ-like... 0.24 OF
MGG_00559T0 No alias tRNA (Uridine-2'-O-)-methyltransferase TRM7... 0.02 OF
MGG_08140T0 No alias AdoMet-dependent rRNA methyltransferase SPB1... 0.06 OF
POW00615 No alias Ribosomal RNA methyltransferase Spb1, domain of unknown... 0.03 OF

Type GO Term Name Evidence Source
MF GO:0008168 methyltransferase activity IEA Interproscan
BP GO:0032259 methylation IEA Interproscan
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Type GO Term Name Evidence Source

No Predicted GO terms available for this sequence
InterPro domains Description Start Stop
IPR002877 rRNA_MeTrfase_FtsJ_dom 21 207
No external refs found!