YJL101C

Description : Gamma glutamylcysteine synthetase; catalyzes the first step in glutathione (GSH) biosynthesis; expression induced by oxidants, cadmium, and mercury; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000003637]

Gene families : OG_03_0000945 (OF) Phylogenetic Tree(s): OG0000945_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: YJL101C
Cluster	HCCA: Cluster_19

Target	Alias	Description	ECC score	Gene Family Method
CAG80183	No alias	Glutamate-cysteine ligase catalytic subunit	0.03	OF
EED77171	No alias	Glutamate-cysteine ligase catalytic subunit	0.02	OF
EGR50607	No alias	Glutamate-cysteine ligase catalytic subunit	0.06	OF
ESU16642	No alias	glutamate-cysteine ligase	0.02	OF
KHC83540	No alias	glutamate-cysteine ligase;Glutamate-cysteine ligase	0.06	OF
MGG_07317T0	No alias	Glutamate-cysteine ligase [Source:UniProtKB/TrEMBL;Acc:G4MV08]	0.02	OF

Type	GO Term	Name	Evidence	Source
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0004357	glutamate-cysteine ligase activity	IEA	Interproscan
BP	GO:0006518	peptide metabolic process	None	Extended
BP	GO:0006575	cellular modified amino acid metabolic process	None	Extended
BP	GO:0006749	glutathione metabolic process	None	Extended
BP	GO:0006750	glutathione biosynthetic process	IEA	Interproscan
BP	GO:0006790	sulfur compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009058	biosynthetic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
MF	GO:0016874	ligase activity	None	Extended
MF	GO:0016879	ligase activity, forming carbon-nitrogen bonds	None	Extended
MF	GO:0016881	acid-amino acid ligase activity	None	Extended
BP	GO:0019184	nonribosomal peptide biosynthetic process	None	Extended
BP	GO:0034641	cellular nitrogen compound metabolic process	None	Extended
BP	GO:0042398	cellular modified amino acid biosynthetic process	None	Extended
BP	GO:0043043	peptide biosynthetic process	None	Extended
BP	GO:0043603	cellular amide metabolic process	None	Extended
BP	GO:0043604	amide biosynthetic process	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044249	cellular biosynthetic process	None	Extended
BP	GO:0044271	cellular nitrogen compound biosynthetic process	None	Extended
BP	GO:0044272	sulfur compound biosynthetic process	None	Extended
BP	GO:0051186	cofactor metabolic process	None	Extended
BP	GO:0051188	cofactor biosynthetic process	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:1901564	organonitrogen compound metabolic process	None	Extended
BP	GO:1901566	organonitrogen compound biosynthetic process	None	Extended
BP	GO:1901576	organic substance biosynthetic process	None	Extended

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Type	GO Term	Name	Evidence	Source
No Predicted GO terms available for this sequence

InterPro domains	Description	Start	Stop
IPR004308	GCS	253	644

External Links

No external refs found!

YJL101C

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation