Description : Gamma glutamylcysteine synthetase; catalyzes the first step in glutathione (GSH) biosynthesis; expression induced by oxidants, cadmium, and mercury; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000003637]
Gene families : OG_03_0000945 (OF) Phylogenetic Tree(s): OG0000945_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
Type | Description | Actions |
---|---|---|
Neighborhood | HRR: YJL101C | |
Cluster | HCCA: Cluster_19 |
Target | Alias | Description | ECC score | Gene Family Method | Actions |
---|---|---|---|---|---|
CAG80183 | No alias | Glutamate-cysteine ligase catalytic subunit | 0.03 | OF | |
EED77171 | No alias | Glutamate-cysteine ligase catalytic subunit | 0.02 | OF | |
EGR50607 | No alias | Glutamate-cysteine ligase catalytic subunit | 0.06 | OF | |
ESU16642 | No alias | glutamate-cysteine ligase | 0.02 | OF | |
KHC83540 | No alias | glutamate-cysteine ligase;Glutamate-cysteine ligase | 0.06 | OF | |
MGG_07317T0 | No alias | Glutamate-cysteine ligase [Source:UniProtKB/TrEMBL;Acc:G4MV08] | 0.02 | OF |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
MF | GO:0004357 | glutamate-cysteine ligase activity | IEA | Interproscan |
BP | GO:0006750 | glutathione biosynthetic process | IEA | Interproscan |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
No Predicted GO terms available for this sequence |
InterPro domains | Description | Start | Stop |
---|---|---|---|
IPR004308 | GCS | 253 | 644 |
No external refs found! |