Description : DNA helicase and DNA-dependent ATPase; involved in DNA repair and checkpoint recovery, needed for proper timing of commitment to meiotic recombination and transition from Meiosis I to II; blocks trinucleotide repeat expansion; affects genome stability; disassembles Rad51p nucleoprotein filaments during meiotic recombination; stimulates activity of the Mus81p-Mms4p endonuclease, independently of Srs2p catalytic activity; functional homolog of human RTEL1 [Source:SGD;Acc:S000003628]
Gene families : OG_03_0004104 (OF) Phylogenetic Tree(s): OG0004104_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
Type | Description | Actions |
---|---|---|
Neighborhood | HRR: YJL092W | |
Cluster | HCCA: Cluster_41 |
Target | Alias | Description | ECC score | Gene Family Method | Actions |
---|---|---|---|---|---|
AFR97736 | No alias | DNA helicase II/ATP-dependent DNA helicase PcrA;UvrD/REP... | 0.05 | OF | |
AOA68569 | No alias | UvrD-like DNA helicase, C-terminal | 0.07 | OF | |
EAA31132 | No alias | UvrD/AddA helicase, N-terminal | 0.03 | OF | |
EFI27904 | No alias | ATP-dependent DNA helicase pcra | 0.05 | OF | |
ESU14946 | No alias | UvrD-like DNA helicase, C-terminal | 0.04 | OF | |
KHC79043 | No alias | DNA helicase II/ATP-dependent DNA helicase... | 0.09 | OF |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
MF | GO:0005524 | ATP binding | IEA | Interproscan |
MF | GO:0016787 | hydrolase activity | IEA | Interproscan |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
No Predicted GO terms available for this sequence |
No external refs found! |