YHR183W

Description : 6-phosphogluconate dehydrogenase (decarboxylating); catalyzes an NADPH regenerating reaction in the pentose phosphate pathway; required for growth on D-glucono-delta-lactone and adaptation to oxidative stress; GND1 has a paralog, GND2, that arose from the whole genome duplication [Source:SGD;Acc:S000001226]

Gene families : OG_03_0000737 (OF) Phylogenetic Tree(s): OG0000737_tree

Sequence : coding (download), protein (download)

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Type	Description	Actions
Neighborhood	HRR: YHR183W
Cluster	HCCA: Cluster_19

Target	Alias	Description	ECC score	Gene Family Method
AFR93599	No alias	6-phosphogluconate dehydrogenase, decarboxylating;NAD...	0.02	OF
AFR94072	No alias	6-phosphogluconate dehydrogenase, decarboxylating...	0.02	OF
AOA68325	No alias	6-phosphogluconate dehydrogenase, C-terminal	0.02	OF
CAG83189	No alias	6-phosphogluconate dehydrogenase, C-terminal	0.03	OF
CAK40566	No alias	6-phosphogluconate dehydrogenase, C-terminal domain	0.02	OF
CBF75018	No alias	hypothetical protein similar to 6-phosphogluconate dehydrogenase	0.04	OF
ESU06391	No alias	6-phosphogluconate dehydrogenase	0.02	OF
KHC84115	No alias	6-phosphogluconate dehydrogenase,...	0.04	OF
SPBC660.16.1	No alias	phosphogluconate dehydrogenase, decarboxylating...	0.03	OF

Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	None	Extended
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0004616	phosphogluconate dehydrogenase (decarboxylating) activity	IEA	Interproscan
MF	GO:0005488	binding	None	Extended
BP	GO:0006091	generation of precursor metabolites and energy	None	Extended
BP	GO:0006098	pentose-phosphate shunt	IEA	Interproscan
BP	GO:0006739	NADP metabolic process	None	Extended
BP	GO:0006740	NADPH regeneration	None	Extended
BP	GO:0006793	phosphorus metabolic process	None	Extended
BP	GO:0006796	phosphate-containing compound metabolic process	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
MF	GO:0016491	oxidoreductase activity	None	Extended
MF	GO:0016614	oxidoreductase activity, acting on CH-OH group of donors	None	Extended
MF	GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	None	Extended
BP	GO:0019637	organophosphate metabolic process	None	Extended
MF	GO:0036094	small molecule binding	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
MF	GO:0048037	cofactor binding	None	Extended
MF	GO:0050661	NADP binding	IEA	Interproscan
MF	GO:0050662	coenzyme binding	None	Extended
BP	GO:0051156	glucose 6-phosphate metabolic process	None	Extended
BP	GO:0055114	oxidation-reduction process	IEA	Interproscan
BP	GO:0071704	organic substance metabolic process	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
BP	GO:1901135	carbohydrate derivative metabolic process	None	Extended
MF	GO:1901265	nucleoside phosphate binding	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended

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Type	GO Term	Name	Evidence	Source
No Predicted GO terms available for this sequence

InterPro domains	Description	Start	Stop
IPR006115	6PGDH_NADP-bd	5	172
IPR006114	6PGDH_C	178	475

External Links

No external refs found!

YHR183W

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation