Description : 6-phosphogluconate dehydrogenase (decarboxylating); catalyzes an NADPH regenerating reaction in the pentose phosphate pathway; required for growth on D-glucono-delta-lactone and adaptation to oxidative stress; GND1 has a paralog, GND2, that arose from the whole genome duplication [Source:SGD;Acc:S000001226]

Gene families : OG_03_0000737 (OF) Phylogenetic Tree(s): OG0000737_tree

Sequence : coding (download), protein (download)

Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type Description Actions
Neighborhood HRR: YHR183W
Cluster HCCA: Cluster_19

Target Alias Description ECC score Gene Family Method Actions
AFR93599 No alias 6-phosphogluconate dehydrogenase, decarboxylating;NAD... 0.02 OF
AFR94072 No alias 6-phosphogluconate dehydrogenase, decarboxylating... 0.02 OF
AOA68325 No alias 6-phosphogluconate dehydrogenase, C-terminal 0.02 OF
CAG83189 No alias 6-phosphogluconate dehydrogenase, C-terminal 0.03 OF
CAK40566 No alias 6-phosphogluconate dehydrogenase, C-terminal domain 0.02 OF
CBF75018 No alias hypothetical protein similar to 6-phosphogluconate dehydrogenase 0.04 OF
ESU06391 No alias 6-phosphogluconate dehydrogenase 0.02 OF
KHC84115 No alias 6-phosphogluconate dehydrogenase,... 0.04 OF
SPBC660.16.1 No alias phosphogluconate dehydrogenase, decarboxylating... 0.03 OF

Type GO Term Name Evidence Source
MF GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity IEA Interproscan
BP GO:0006098 pentose-phosphate shunt IEA Interproscan
MF GO:0050661 NADP binding IEA Interproscan
BP GO:0055114 oxidation-reduction process IEA Interproscan
Type GO Term Name Evidence Source

No Predicted GO terms available for this sequence

InterPro domains Description Start Stop
IPR006115 6PGDH_NADP-bd 5 172
IPR006114 6PGDH_C 178 475
No external refs found!