Description : Protein involved in regulation of sterol biosynthesis; specifically stabilizes Hmg2p, one of two HMG-CoA isoenzymes that catalyze the rate-limiting step in sterol biosynthesis; forms foci at the nuclear periphery upon DNA replication stress; relocalizes to the cytosol in response to hypoxia; homolog of mammalian INSIG proteins; NSG1 has a paralog, NSG2, that arose from the whole genome duplication [Source:SGD;Acc:S000001175]
Gene families : OG_03_0004018 (OF) Phylogenetic Tree(s): OG0004018_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
|Target||Alias||Description||ECC score||Gene Family Method||Actions|
|SPCC306.05c.1||No alias||INSIG domain protein [Source:PomBase;Acc:SPCC306.05c]||0.03||OF|
No GO annotation available for this sequence
No Predicted GO terms available for this sequence
|No external refs found!|