YHR057C

Description : Peptidyl-prolyl cis-trans isomerase (cyclophilin); catalyzes the cis-trans isomerization of peptide bonds N-terminal to proline residues; potential role in the secretory pathway; seamless-GFP and mCherry fusion proteins localize to the vacuole, while SWAT-GFP fusion localizes to both the endoplasmic reticulum and vacuole; suppresses toxicity of slow-folding human Z-type alpha1-antitrypsin variant associated with liver cirrhosis and emphysema [Source:SGD;Acc:S000001099]

Gene families : OG_03_0000094 (OF) Phylogenetic Tree(s): OG0000094_tree

Sequence : coding (download), protein (download)

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Type	Description	Actions
Neighborhood	HRR: YHR057C
Cluster	HCCA: Cluster_50

Target	Alias	Description	ECC score	Gene Family Method
AFR93130	No alias	peptidyl-prolyl cis-trans isomerase;Cyclophilin type...	0.03	OF
AFR96711	No alias	peptidyl-prolyl cis-trans isomerase B;Cyclophilin type...	0.01	OF
CAG81980	No alias	Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain	0.03	OF
CAK48212	No alias	cyclophilin-like peptidyl prolyl cis-trans isomerase...	0.02	OF
CBF84775	No alias	Peptidyl-prolyl cis-trans isomerase H	0.02	OF
EAL87466	No alias	peptidyl-prolyl cis-trans isomerase	0.03	OF
EAL92828	No alias	peptidyl-prolyl cis-trans isomerase/cyclophilin, putative	0.02	OF
EAU82113	No alias	cyclophilin	0.03	OF
EAU91055	No alias	peptidylprolyl isomerase B	0.02	OF
EGR47523	No alias	Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain	0.02	OF
EGR48175	No alias	Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain	0.02	OF
ESA44269	No alias	Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain	0.01	OF
ESU06003	No alias	Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain	0.02	OF
KHC79156	No alias	peptidyl-prolyl cis-trans isomerase B (cyclophilin...	0.03	OF
POW04570	No alias	Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain	0.04	OF
POW06012	No alias	Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain	0.04	OF

Type	GO Term	Name	Evidence	Source
BP	GO:0000413	protein peptidyl-prolyl isomerization	IEA	Interproscan
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003755	peptidyl-prolyl cis-trans isomerase activity	IEA	Interproscan
MF	GO:0003824	catalytic activity	None	Extended
BP	GO:0006464	cellular protein modification process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
MF	GO:0016853	isomerase activity	None	Extended
MF	GO:0016859	cis-trans isomerase activity	None	Extended
BP	GO:0018193	peptidyl-amino acid modification	None	Extended
BP	GO:0018208	peptidyl-proline modification	None	Extended
BP	GO:0019538	protein metabolic process	None	Extended
BP	GO:0036211	protein modification process	None	Extended
BP	GO:0043170	macromolecule metabolic process	None	Extended
BP	GO:0043412	macromolecule modification	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044260	cellular macromolecule metabolic process	None	Extended
BP	GO:0044267	cellular protein metabolic process	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
MF	GO:0140096	catalytic activity, acting on a protein	None	Extended
BP	GO:1901564	organonitrogen compound metabolic process	None	Extended

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Type	GO Term	Name	Evidence	Source
No Predicted GO terms available for this sequence

InterPro domains	Description	Start	Stop
IPR002130	Cyclophilin-type_PPIase_dom	40	197

External Links

No external refs found!

YHR057C

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation