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  5. YHL003C

YHL003C


Description : Ceramide synthase component; involved in synthesis of ceramide from C26(acyl)-coenzyme A and dihydrosphingosine or phytosphingosine, functionally equivalent to Lac1p; forms ER foci upon DNA replication stress; homolog of human CERS2, a tumor metastasis suppressor gene whose silencing enhances invasion/metastasis of prostate cancer cells; LAG1 has a paralog, LAC1, that arose from the whole genome duplication [Source:SGD;Acc:S000000995]


Gene families : OG_03_0001890 (OF) Phylogenetic Tree(s): OG0001890_tree

Sequence : coding (download), protein (download)


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Type Description Actions
Neighborhood HRR: YHL003C
Cluster HCCA: Cluster_55

Target Alias Description ECC score Gene Family Method Actions
CAK96890 No alias TLC domain 0.02 OF
CBF86909 No alias ceramide synthase LagA 0.03 OF
EAA27759 No alias TRAM/LAG1/CLN8 homology domain 0.06 OF
EAU84867 No alias longevity-assurance protein 1 0.04 OF
EDO00725 No alias TRAM/LAG1/CLN8 homology domain 0.02 OF
KHC71083 No alias acyl-CoA-dependent ceramide synthase;TRAM1-like... 0.06 OF

Type GO Term Name Evidence Source
CC GO:0016021 integral component of membrane IEA Interproscan
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Type GO Term Name Evidence Source

No Predicted GO terms available for this sequence
InterPro domains Description Start Stop
IPR013599 TRAM1 110 167
IPR006634 TLC-dom 173 377
No external refs found!