YGR246C

Description : TFIIIB B-related factor; one of three subunits of RNA polymerase III transcription initiation factor TFIIIB, binds TFIIIC and TBP and recruits RNA pol III to promoters, amino-terminal half is homologous to TFIIB; mutations in human homolog are associated with autosomal recessive cerebellar-facial-dental syndrome [Source:SGD;Acc:S000003478]

Gene families : OG_03_0002225 (OF) Phylogenetic Tree(s): OG0002225_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: YGR246C
Cluster	HCCA: Cluster_61

Target	Alias	Description	ECC score	Gene Family Method
CAG79933	No alias	Brf1, TBP-binding domain	0.03	OF
CAK44279	No alias	Brf1-like TBP-binding domain	0.02	OF
EGR52397	No alias	Brf1, TBP-binding domain	0.02	OF
EJF60939	No alias	Brf1-like TBP-binding domain	0.02	OF
ESU09153	No alias	Transcription factor TFIIB, cyclin-like domain	0.03	OF
POW08553	No alias	Brf1, TBP-binding domain;Zinc finger,...	0.02	OF
SPBC13E7.10c.1	No alias	transcription factor TFIIIB complex subunit Brf1...	0.03	OF

Type	GO Term	Name	Evidence	Source
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0005488	binding	None	Extended
MF	GO:0005515	protein binding	None	Extended
MF	GO:0008134	transcription factor binding	None	Extended
MF	GO:0017025	TBP-class protein binding	IEA	Interproscan
MF	GO:0140296	general transcription initiation factor binding	None	Extended

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Type	GO Term	Name	Evidence	Source
No Predicted GO terms available for this sequence

InterPro domains	Description	Start	Stop
IPR013137	Znf_TFIIB	3	45
IPR011665	BRF1_TBP-bd_dom	463	595
IPR013150	TFIIB_cyclin	182	255
IPR013150	TFIIB_cyclin	89	157

External Links

No external refs found!

YGR246C

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation