YGR162W

Description : Translation initiation factor eIF4G; subunit of the mRNA cap-binding protein complex (eIF4F) that also contains eIF4E (Cdc33p); interacts with Pab1p and with eIF4A (Tif1p); also has a role in biogenesis of the large ribosomal subunit; TIF4631 has a paralog, TIF4632, that arose from the whole genome duplication [Source:SGD;Acc:S000003394]

Gene families : OG_03_0000458 (OF) Phylogenetic Tree(s): OG0000458_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: YGR162W
Cluster	HCCA: Cluster_54

Target	Alias	Description	ECC score	Gene Family Method
AFR92519	No alias	translation initiation factor 4G;Eukaryotic translation...	0.09	OF
AOA66685	No alias	Eukaryotic translation initiation factor 4G1,...	0.11	OF
CAG81749	No alias	Eukaryotic translation initiation factor 4G1,...	0.09	OF
CAK42934	No alias	hypothetical protein	0.11	OF
CAK42935	No alias	MIF4G domain	0.11	OF
CBF70267	No alias	eukaryotic translation initiation factor subunit eIF-4F, putative	0.05	OF
EAL93245	No alias	eukaryotic translation initiation factor subunit eIF-4F, putative	0.15	OF
EDN90708	No alias	MIF4G-like, type 3	0.04	OF
EGR53003	No alias	MIF4G-like, type 3	0.03	OF
EJF57549	No alias	MA3 domain	0.07	OF
ESA43154	No alias	MIF4G-like, type 3	0.12	OF
ESU11382	No alias	MIF4G-like, type 3	0.04	OF
KHC81903	No alias	translation initiation factor 4G;MIF4G domain;Eukaryotic...	0.06	OF
MGG_06396T0	No alias	Putative uncharacterized protein...	0.06	OF
POW02905	No alias	MIF4G-like, type 3	0.02	OF
SPAC17C9.03.1	No alias	translation initiation factor eIF4G...	0.13	OF

Type	GO Term	Name	Evidence	Source
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003676	nucleic acid binding	None	Extended
MF	GO:0003723	RNA binding	IEA	Interproscan
MF	GO:0005488	binding	None	Extended
MF	GO:0005515	protein binding	IEA	Interproscan
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended

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Type	GO Term	Name	Evidence	Source
No Predicted GO terms available for this sequence

InterPro domains	Description	Start	Stop
IPR003890	MIF4G-like_typ-3	607	850
IPR022745	eIF4G1_eIF4E-bd	401	469

External Links

No external refs found!

YGR162W

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation