YGR104C

Description : Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; essential for transcriptional regulation; required for proper termination of transcription for some genes; involved in telomere maintenance [Source:SGD;Acc:S000003336]

Gene families : OG_03_0008490 (OF) Phylogenetic Tree(s): OG0008490_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: YGR104C
Cluster	HCCA: Cluster_66

Target	Alias	Description	ECC score	Gene Family Method	Actions
CAG83514	No alias	Mediator complex, subunit Med18	0.02	OF
KHC81958	No alias	hypothetical protein;Med18 protein	0.03	OF

Type	GO Term	Name	Evidence	Source
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003712	transcription coregulator activity	IEA	Interproscan
CC	GO:0005575	cellular_component	None	Extended
BP	GO:0006355	regulation of transcription, DNA-templated	None	Extended
BP	GO:0006357	regulation of transcription by RNA polymerase II	IEA	Interproscan
BP	GO:0008150	biological_process	None	Extended
BP	GO:0009889	regulation of biosynthetic process	None	Extended
BP	GO:0010468	regulation of gene expression	None	Extended
BP	GO:0010556	regulation of macromolecule biosynthetic process	None	Extended
CC	GO:0016592	mediator complex	IEA	Interproscan
BP	GO:0019219	regulation of nucleobase-containing compound metabolic process	None	Extended
BP	GO:0019222	regulation of metabolic process	None	Extended
BP	GO:0031323	regulation of cellular metabolic process	None	Extended
BP	GO:0031326	regulation of cellular biosynthetic process	None	Extended
CC	GO:0032991	protein-containing complex	None	Extended
BP	GO:0050789	regulation of biological process	None	Extended
BP	GO:0050794	regulation of cellular process	None	Extended
BP	GO:0051171	regulation of nitrogen compound metabolic process	None	Extended
BP	GO:0051252	regulation of RNA metabolic process	None	Extended
BP	GO:0060255	regulation of macromolecule metabolic process	None	Extended
BP	GO:0065007	biological regulation	None	Extended
BP	GO:0080090	regulation of primary metabolic process	None	Extended
MF	GO:0140110	transcription regulator activity	None	Extended
BP	GO:1903506	regulation of nucleic acid-templated transcription	None	Extended
BP	GO:2000112	regulation of cellular macromolecule biosynthetic process	None	Extended
BP	GO:2001141	regulation of RNA biosynthetic process	None	Extended

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Type	GO Term	Name	Evidence	Source
No Predicted GO terms available for this sequence

InterPro domains	Description	Start	Stop
IPR019095	Mediator_Med18	3	299

External Links

No external refs found!

YGR104C

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation