Description : Separase, a caspase-like cysteine protease; promotes sister chromatid separation by mediating dissociation of the cohesin Scc1p from chromatin; inhibits protein phosphatase 2A-Cdc55p to promote mitotic exit; inhibited by Pds1p; relative distribution to the nucleus increases upon DNA replication stress [Source:SGD;Acc:S000003330]
Gene families : OG_03_0002614 (OF) Phylogenetic Tree(s): OG0002614_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
Type | Description | Actions |
---|---|---|
Neighborhood | HRR: YGR098C | |
Cluster | HCCA: Cluster_12 |
Target | Alias | Description | ECC score | Gene Family Method | Actions |
---|---|---|---|---|---|
AFR93064 | No alias | separase;Peptidase family C50 | 0.03 | OF | |
AOA66266 | No alias | Peptidase family C50 | 0.09 | OF | |
CAG81925 | No alias | Peptidase family C50 | 0.12 | OF | |
CAL00243 | No alias | Peptidase family C50 | 0.03 | OF | |
CBF78027 | No alias | Separin | 0.02 | OF | |
EAA27354 | No alias | Peptidase family C50 | 0.09 | OF | |
EAL91630 | No alias | separin, putative | 0.15 | OF | |
EAU89520 | No alias | cysteine-type endopeptidase | 0.03 | OF | |
EDO04859 | No alias | Peptidase family C50 | 0.1 | OF | |
EGR46037 | No alias | Peptidase family C50 | 0.02 | OF | |
EJF58174 | No alias | Peptidase family C50 | 0.02 | OF | |
KHC82952 | No alias | separase;Peptidase family C50 | 0.14 | OF | |
MGG_06245T0 | No alias | Separin [Source:UniProtKB/TrEMBL;Acc:G4N8I2] | 0.03 | OF | |
SPCC5E4.04.1 | No alias | separase/separin [Source:PomBase;Acc:SPCC5E4.04] | 0.13 | OF |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
No GO annotation available for this sequence |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
No Predicted GO terms available for this sequence |
No InterPro domains available for this sequence
No external refs found! |