Description : Eisosome core component; eisosomes are large immobile cell cortex structures associated with endocytosis; detected in phosphorylated state in mitochondria; phosphorylated on Thr233 upon Pkc1p hyperactivation in a Slt2p MAPK-dependent fashion; null mutant shows activation of Pkc1p/Ypk1p stress resistance pathways; member of BAR domain family; protein increases in abundance and relocalizes from plasma membrane to cytoplasm upon DNA replication stress [Source:SGD;Acc:S000003318]
Gene families : OG_03_0000556 (OF) Phylogenetic Tree(s): OG0000556_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
Type | Description | Actions |
---|---|---|
Neighborhood | HRR: YGR086C | |
Cluster | HCCA: Cluster_45 |
Target | Alias | Description | ECC score | Gene Family Method | Actions |
---|---|---|---|---|---|
AOA65970 | No alias | Eisosome component PIL1/LSP1 | 0.04 | OF | |
AOA68823 | No alias | Eisosome component PIL1/LSP1 | 0.05 | OF | |
CAK45097 | No alias | Eisosome component PIL1 | 0.03 | OF | |
CAK45909 | No alias | Eisosome component PIL1 | 0.03 | OF | |
CBF81101 | No alias | primary component of eisosomes | 0.03 | OF | |
EAA35806 | No alias | Eisosome component PIL1/LSP1 | 0.03 | OF | |
EAA36435 | No alias | Eisosome component PIL1/LSP1 | 0.03 | OF | |
EAL88605 | No alias | cell wall integrity signaling protein Lsp1/Pil1, putative | 0.05 | OF | |
EAL88683 | No alias | conserved hypothetical protein | 0.03 | OF | |
EDN93360 | No alias | Eisosome component PIL1/LSP1 | 0.03 | OF | |
EGR47420 | No alias | Eisosome component PIL1/LSP1 | 0.04 | OF | |
ESU06149 | No alias | Eisosome component PIL1/LSP1 | 0.03 | OF | |
KHC81707 | No alias | sphingolipid long chain base-responsive protein... | 0.04 | OF | |
KHC83245 | No alias | hypothetical protein;Eisosome component PIL1 | 0.04 | OF | |
MGG_00153T0 | No alias | Sphingolipid long chain base-responsive protein LSP1... | 0.03 | OF | |
MGG_11731T0 | No alias | Sphingolipid long chain base-responsive protein LSP1... | 0.02 | OF | |
SPCC736.15.1 | No alias | eisosome BAR domain protein Pil1 [Source:PomBase;Acc:SPCC736.15] | 0.13 | OF |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
No GO annotation available for this sequence |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
No Predicted GO terms available for this sequence |
InterPro domains | Description | Start | Stop |
---|---|---|---|
IPR028245 | PIL1/LSP1 | 1 | 264 |
No external refs found! |