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  5. YGR060W

YGR060W


Description : C-4 methyl sterol oxidase; catalyzes the first of three steps required to remove two C-4 methyl groups from an intermediate in ergosterol biosynthesis; mutants accumulate the sterol intermediate 4,4-dimethylzymosterol; human MSMO1 functionally complements the growth defect caused by repression of ERG25 expression [Source:SGD;Acc:S000003292]


Gene families : OG_03_0000878 (OF) Phylogenetic Tree(s): OG0000878_tree

Sequence : coding (download), protein (download)


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Type Description Actions
Neighborhood HRR: YGR060W
Cluster HCCA: Cluster_17

Target Alias Description ECC score Gene Family Method Actions
AFR97939 No alias methylsterol monooxygenase;Fatty acid hydroxylase superfamily 0.16 OF
AOA68717 No alias Fatty acid hydroxylase 0.08 OF
CAG78088 No alias Fatty acid hydroxylase 0.04 OF
CAK38397 No alias Fatty acid hydroxylase superfamily 0.05 OF
CBF79344 No alias C-4 methyl sterol oxidase Erg25, putative 0.07 OF
CBF84688 No alias C-4 methyl sterol oxidase, putative 0.05 OF
EAL84630 No alias C-4 methyl sterol oxidase Erg25, putative 0.08 OF
EAL84924 No alias C-4 methyl sterol oxidase, putative 0.03 OF
EAU83482 No alias C-4 methyl sterol oxidase 0.13 OF
EJF60811 No alias Fatty acid hydroxylase superfamily 0.06 OF
ESA42889 No alias Fatty acid hydroxylase 0.04 OF
ESA42890 No alias Fatty acid hydroxylase 0.03 OF
ESU16462 No alias C-4 methylsterol oxidase 0.08 OF
KHC71199 No alias C-4 methylsterol oxidase;Fatty acid hydroxylase superfamily 0.02 OF
KHC78100 No alias methylsterol monooxygenase;Fatty acid hydroxylase superfamily 0.22 OF
SPAC630.08c.1 No alias C-4 methylsterol oxidase Erg25 (predicted)... 0.08 OF

Type GO Term Name Evidence Source
MF GO:0005506 iron ion binding IEA Interproscan
BP GO:0008610 lipid biosynthetic process IEA Interproscan
MF GO:0016491 oxidoreductase activity IEA Interproscan
BP GO:0055114 oxidation-reduction process IEA Interproscan
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Type GO Term Name Evidence Source

No Predicted GO terms available for this sequence
InterPro domains Description Start Stop
IPR006694 Fatty_acid_hydroxylase 147 282
No external refs found!