Description : Protein that mediates sphingolipid homeostasis; evolutionarily conserved, required for resistance to agents that induce unfolded protein response; Orm1p and Orm2p together control membrane biogenesis by coordinating lipid homeostasis with protein quality control; ORM1 has a paralog, ORM2, that arose from the whole genome duplication [Source:SGD;Acc:S000003270]
Gene families : OG_03_0001850 (OF) Phylogenetic Tree(s): OG0001850_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
Type | Description | Actions |
---|---|---|
Neighborhood | HRR: YGR038W | |
Cluster | HCCA: Cluster_39 |
Target | Alias | Description | ECC score | Gene Family Method | Actions |
---|---|---|---|---|---|
AFR98694 | No alias | hypothetical protein;ORMDL family | 0.02 | OF | |
EGR47806 | No alias | ORMDL family | 0.02 | OF |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
CC | GO:0005789 | endoplasmic reticulum membrane | IEA | Interproscan |
CC | GO:0016021 | integral component of membrane | IEA | Interproscan |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
No Predicted GO terms available for this sequence |
InterPro domains | Description | Start | Stop |
---|---|---|---|
IPR007203 | ORMDL | 74 | 209 |
No external refs found! |