Description : Hexokinase isoenzyme 2; phosphorylates glucose in cytosol; predominant hexokinase during growth on glucose; represses expression of HXK1, GLK1, induces expression of its own gene; antiapoptotic; phosphorylation/dephosphorylation at Ser14 by kinase Snf1p, phosphatase Glc7p-Reg1p regulates nucleocytoplasmic shuttling of Hxk2p; functions downstream of Sit4p in control of cell cycle, mitochondrial function, oxidative stress resistance, chronological lifespan; has paralog HXK1 [Source:SGD;Acc:S000003222]

Gene families : OG_03_0000142 (OF) Phylogenetic Tree(s): OG0000142_tree

Sequence : coding (download), protein (download)

Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type Description Actions
Neighborhood HRR: YGL253W
Cluster HCCA: Cluster_8

Target Alias Description ECC score Gene Family Method Actions
AFR93275 No alias hexokinase;Hexokinase 0.03 OF
AOA69936 No alias Hexokinase, N-terminal 0.31 OF
CAK48869 No alias hexokinase hxk-Aspergillus niger 0.02 OF
EAL87682 No alias hexokinase Kxk, putative 0.03 OF
EDO02930 No alias Hexokinase, N-terminal 0.02 OF
ESU05689 No alias hexokinase 0.07 OF
KHC71396 No alias hexokinase;Hexokinase 0.14 OF
MGG_09289T0 No alias Hexokinase [Source:UniProtKB/TrEMBL;Acc:G4MQN9] 0.04 OF
SPAC4F8.07c.1 No alias hexokinase 2 [Source:PomBase;Acc:SPAC4F8.07c] 0.1 OF

Type GO Term Name Evidence Source
MF GO:0005524 ATP binding IEA Interproscan
BP GO:0005975 carbohydrate metabolic process IEA Interproscan
MF GO:0016773 phosphotransferase activity, alcohol group as acceptor IEA Interproscan
Type GO Term Name Evidence Source

No Predicted GO terms available for this sequence

InterPro domains Description Start Stop
IPR022673 Hexokinase_C 227 470
IPR022672 Hexokinase_N 27 221
No external refs found!