Description : Nuclear envelope protein that acts as a recycling factor; mediates the nuclear export of Srp1p (importin alpha) back to the cytoplasm after its import substrates have been released into the nucleoplasm, thereby allowing the participation of Srp1p in multiple rounds of nuclear import; required for accurate chromosome segregation; homolog of metazoan CAS and human CSE1L, overexpression of which is implicated in cancer progression [Source:SGD;Acc:S000003207]
Gene families : OG_03_0002893 (OF) Phylogenetic Tree(s): OG0002893_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
Type | Description | Actions |
---|---|---|
Neighborhood | HRR: YGL238W | |
Cluster | HCCA: Cluster_63 |
Target | Alias | Description | ECC score | Gene Family Method | Actions |
---|---|---|---|---|---|
AFR97904 | No alias | importin-alpha export receptor;CAS/CSE protein,... | 0.07 | OF | |
AOA68271 | No alias | Importin-beta, N-terminal domain | 0.07 | OF | |
CAG79236 | No alias | Importin-beta, N-terminal domain | 0.08 | OF | |
CAL00938 | No alias | Cse1 | 0.06 | OF | |
CBF71053 | No alias | KapEPutative uncharacterized protein | 0.07 | OF | |
EAA31630 | No alias | Importin-beta, N-terminal domain | 0.06 | OF | |
EAL85638 | No alias | chromosome segregation protein Cse1, putative | 0.1 | OF | |
EAU80449 | No alias | importin alpha re-exporter | 0.06 | OF | |
EDN91166 | No alias | Importin-beta, N-terminal domain | 0.08 | OF | |
EGR52141 | No alias | Exportin-2, C-terminal | 0.07 | OF | |
ESU13381 | No alias | Exportin-2, central domain | 0.08 | OF | |
KHC83526 | No alias | hypothetical protein;Cse1;"CAS/CSE protein,... | 0.06 | OF | |
MGG_03994T0 | No alias | Importin alpha re-exporter [Source:UniProtKB/TrEMBL;Acc:G4NGY3] | 0.14 | OF | |
POW10230 | No alias | Importin-beta, N-terminal domain;Exportin-2, central domain | 0.07 | OF | |
SPBC30B4.05.1 | No alias | karyopherin Kap109 [Source:PomBase;Acc:SPBC30B4.05] | 0.05 | OF |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
MF | GO:0005515 | protein binding | IEA | Interproscan |
BP | GO:0006886 | intracellular protein transport | IEA | Interproscan |
MF | GO:0008536 | Ran GTPase binding | IEA | Interproscan |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
No Predicted GO terms available for this sequence |
No external refs found! |