Description : Subunit of the heterodimeric FACT complex (Spt16p-Pob3p); FACT associates with chromatin via interaction with Nhp6Ap and Nhp6Bp, and reorganizes nucleosomes to facilitate access to DNA by RNA and DNA polymerases; specifically required for diauxic shift-induced H2B deposition onto rDNA genes; mutations cause reduced nucleosome occupancy over highly transcribed regions; coregulates transcription with Mot1p through preinitiation complex assembly and nucleosome organization [Source:SGD;Acc:S000003175]
Gene families : OG_03_0002203 (OF) Phylogenetic Tree(s): OG0002203_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
Type | Description | Actions |
---|---|---|
Neighborhood | HRR: YGL207W | |
Cluster | HCCA: Cluster_59 |
Target | Alias | Description | ECC score | Gene Family Method | Actions |
---|---|---|---|---|---|
AFR97928 | No alias | FACT complex subunit SPT16;FACT complex subunit SPT16... | 0.05 | OF | |
AOA65557 | No alias | Peptidase M24 | 0.1 | OF | |
CAG81019 | No alias | Peptidase M24 | 0.12 | OF | |
CAK45170 | No alias | Histone chaperone Rttp106-like | 0.06 | OF | |
CBF80864 | No alias | FACT complex subunit spt16 | 0.09 | OF | |
EAA32294 | No alias | FACT complex subunit Spt16 domain | 0.07 | OF | |
EAL88480 | No alias | transcription elongation complex subunit (Cdc68) | 0.04 | OF | |
EAU88389 | No alias | FACT complex subunit SPT16 | 0.03 | OF | |
EDO02377 | No alias | FACT complex subunit Spt16 domain | 0.07 | OF | |
EED55015 | No alias | transcription elongation complex subunit (Cdc68) | 0.02 | OF | |
EGR50622 | No alias | FACT complex subunit Spt16, N-terminal lobe domain | 0.1 | OF | |
ESU16705 | No alias | FACT complex subunit SPT16 | 0.08 | OF | |
KHC76722 | No alias | FACT complex subunit SPT16;Metallopeptidase family... | 0.08 | OF | |
MGG_07316T0 | No alias | FACT complex subunit spt-16 [Source:UniProtKB/TrEMBL;Acc:G4MV07] | 0.07 | OF | |
SPBP8B7.19.1 | No alias | FACT complex subunit Spt16 [Source:PomBase;Acc:SPBP8B7.19] | 0.09 | OF |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
No GO annotation available for this sequence |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
No Predicted GO terms available for this sequence |
No external refs found! |