Description : Subunit of a heterodimeric guanine nucleotide exchange factor (GEF); subunit of the Mon1-Ccz1 GEF complex which stimulates nucleotide exchange and activation of Ypt7p, a Rab family GTPase involved in membrane tethering and fusion events at the late endosome and vacuole; GEF activity is stimulated by membrane association and anionic phospholipids; role in localizing Ypt7p to the vacuolar membrane; required for autophagy, the CVT pathway and mitophagy; potential Cdc28 substrate [Source:SGD;Acc:S000003092]

Gene families : OG_03_0001948 (OF) Phylogenetic Tree(s): OG0001948_tree

Sequence : coding (download), protein (download)

Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type Description Actions
Neighborhood HRR: YGL124C
Cluster HCCA: Cluster_23

Target Alias Description ECC score Gene Family Method Actions
CBF86164 No alias Vacuolar fusion protein mon1 0.02 OF
EAL87594 No alias conserved hypothetical protein 0.02 OF
EDO00110 No alias Vacuolar fusion protein Mon1 0.01 OF
ESU13277 No alias Vacuolar fusion protein Mon1 0.02 OF
SPAC1D4.03c.1 No alias autophagy associated protein Aut12 (predicted)... 0.04 OF

Type GO Term Name Evidence Source
BP GO:0006623 protein targeting to vacuole IEA Interproscan
Type GO Term Name Evidence Source

No Predicted GO terms available for this sequence

InterPro domains Description Start Stop
IPR004353 Mon1 181 643
No external refs found!