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  5. YGL037C

YGL037C


Description : Nicotinamidase that converts nicotinamide to nicotinic acid; part of the NAD(+) salvage pathway; required for life span extension by calorie restriction; lacks a peroxisomal targeting signal but is imported into peroxisomes via binding to Gpd1p; PNC1 expression responds to all known stimuli that extend replicative life span; protein increases in abundance and relative distribution to cytoplasmic foci decreases upon DNA replication stress [Source:SGD;Acc:S000003005]


Gene families : OG_03_0003278 (OF) Phylogenetic Tree(s): OG0003278_tree

Sequence : coding (download), protein (download)


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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood HRR: YGL037C
Cluster HCCA: Cluster_45

Target Alias Description ECC score Gene Family Method Actions
EAU92579 No alias pyrazinamidase/nicotinamidase 0.02 OF
KHC72023 No alias nicotinamidase;Isochorismatase family 0.03 OF

Type GO Term Name Evidence Source
MF GO:0003824 catalytic activity IEA Interproscan
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Type GO Term Name Evidence Source

No Predicted GO terms available for this sequence
InterPro domains Description Start Stop
IPR000868 Isochorismatase-like 3 193
No external refs found!