Description : Activator of anaphase-promoting complex/cyclosome (APC/C); antagonist of the spindle assembly checkpoint; directs ubiquitination of cyclins resulting in mitotic exit; targets the APC/C to specific substrates including: Cdc20p, Ase1p, Cin8p, Fin1p and Clb5p; partially active in metaphase, and fully active in anaphase; cell-cycle regulated [Source:SGD;Acc:S000002971]

Gene families : OG_03_0000274 (OF) Phylogenetic Tree(s): OG0000274_tree

Sequence : coding (download), protein (download)

Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type Description Actions
Neighborhood HRR: YGL003C
Cluster HCCA: Cluster_3

Target Alias Description ECC score Gene Family Method Actions
CBF88730 No alias cell division cycle protein Cdc20, putative 0.03 OF
EGR47182 No alias Anaphase-promoting complex subunit 4, WD40 domain 0.02 OF
KHC81121 No alias hypothetical protein;Anaphase-promoting complex subunit... 0.03 OF

Type GO Term Name Evidence Source
MF GO:0005515 protein binding IEA Interproscan
Type GO Term Name Evidence Source

No Predicted GO terms available for this sequence

InterPro domains Description Start Stop
IPR001680 WD40_repeat 506 543
IPR001680 WD40_repeat 419 458
IPR024977 Apc4_WD40_dom 275 354
No external refs found!