YFR053C

Description : Hexokinase isoenzyme 1; a cytosolic protein that catalyzes phosphorylation of glucose during glucose metabolism; expression is highest during growth on non-glucose carbon sources; glucose-induced repression involves hexokinase Hxk2p; HXK1 has a paralog, HXK2, that arose from the whole genome duplication [Source:SGD;Acc:S000001949]

Gene families : OG_03_0000142 (OF) Phylogenetic Tree(s): OG0000142_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: YFR053C
Cluster	HCCA: Cluster_17

Target	Alias	Description	ECC score	Gene Family Method
AOA65928	No alias	Hexokinase, N-terminal	0.03	OF
CAK41311	No alias	glucokinase glkA-Aspergillus niger	0.1	OF
CBF84304	No alias	conserved hypothetical protein similar to hexokinase	0.02	OF
EAA35500	No alias	Hexokinase, N-terminal	0.03	OF
EAU84941	No alias	hexokinase	0.04	OF
EED48784	No alias	hexokinase Kxk, putative	0.02	OF
EGR46560	No alias	Hexokinase, C-terminal	0.03	OF
ESU10275	No alias	Hexokinase, N-terminal	0.03	OF
ESU14524	No alias	glucokinase	0.02	OF
KHC70602	No alias	hexokinase;Hexokinase	0.12	OF
KHC71396	No alias	hexokinase;Hexokinase	0.06	OF
KHC73583	No alias	hexokinase;Hexokinase	0.03	OF
MGG_03041T0	No alias	Glucokinase [Source:UniProtKB/TrEMBL;Acc:G5EHQ5]	0.03	OF
MGG_09289T0	No alias	Hexokinase [Source:UniProtKB/TrEMBL;Acc:G4MQN9]	0.03	OF

Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	None	Extended
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0005488	binding	None	Extended
MF	GO:0005524	ATP binding	IEA	Interproscan
BP	GO:0005975	carbohydrate metabolic process	IEA	Interproscan
MF	GO:0008144	drug binding	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
MF	GO:0016740	transferase activity	None	Extended
MF	GO:0016772	transferase activity, transferring phosphorus-containing groups	None	Extended
MF	GO:0016773	phosphotransferase activity, alcohol group as acceptor	IEA	Interproscan
MF	GO:0017076	purine nucleotide binding	None	Extended
MF	GO:0030554	adenyl nucleotide binding	None	Extended
MF	GO:0032553	ribonucleotide binding	None	Extended
MF	GO:0032555	purine ribonucleotide binding	None	Extended
MF	GO:0032559	adenyl ribonucleotide binding	None	Extended
MF	GO:0035639	purine ribonucleoside triphosphate binding	None	Extended
MF	GO:0036094	small molecule binding	None	Extended
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043168	anion binding	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:0097367	carbohydrate derivative binding	None	Extended
MF	GO:1901265	nucleoside phosphate binding	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended

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Type	GO Term	Name	Evidence	Source
No Predicted GO terms available for this sequence

InterPro domains	Description	Start	Stop
IPR022673	Hexokinase_C	227	469
IPR022672	Hexokinase_N	27	221

External Links

No external refs found!

YFR053C

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation