Description : Scaffold protein involved in the formation of early endocytic sites; putative regulator of cytokinesis; homo-oligomerization is required for localization to and organization of endocytic sites; has a network of interactions with other endocytic proteins; binds membranes in a ubiquitin-dependent manner; may also bind ubiquitinated membrane-associated proteins; interacts with Cmk2 and functions upstream of CMK2 in regulating non-apoptotic cell death; homolog of mammalian Eps15 [Source:SGD;Acc:S000000143]

Gene families : OG_03_0001622 (OF) Phylogenetic Tree(s): OG0001622_tree

Sequence : coding (download), protein (download)

Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type Description Actions
Neighborhood HRR: YBL047C
Cluster HCCA: Cluster_56

Target Alias Description ECC score Gene Family Method Actions
AFR94125 No alias UBA/TS-N domain-containing... 0.07 OF
AOA67920 No alias EH domain 0.08 OF
CAG82523 No alias EH domain 0.12 OF
CAK43733 No alias Cytoskeletal-regulatory complex EF hand 0.06 OF
CBF89737 No alias EF hand domain protein 0.06 OF
EAA33988 No alias EH domain 0.05 OF
EAL87966 No alias EF hand domain protein 0.09 OF
EAU88413 No alias UBA/TS-N domain-containing protein 0.04 OF
EDN96623 No alias Ubiquitin-associated domain 0.02 OF
EGR52341 No alias EH domain 0.08 OF
ESU11112 No alias EH domain 0.04 OF
KHC83895 No alias hypothetical protein;UBA/TS-N... 0.07 OF
MGG_06649T0 No alias EF hand domain-containing protein... 0.03 OF
SPBC800.10c.1 No alias EPS15 repeat family actin cortical patch component... 0.1 OF
SPBC83.01.1 No alias UBA/EH/EF hand domain protein Ucp8 [Source:PomBase;Acc:SPBC83.01] 0.03 OF

Type GO Term Name Evidence Source
MF GO:0005515 protein binding IEA Interproscan
Type GO Term Name Evidence Source

No Predicted GO terms available for this sequence

InterPro domains Description Start Stop
IPR015940 UBA 1345 1377
IPR000261 EH_dom 11 93
IPR000261 EH_dom 130 220
IPR000261 EH_dom 278 360
No external refs found!